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interleukin 1 receptor type 1

Summary

Gene Symbol

IL1R1

Aliases

CD121A
D2S1473
interleukin-1 receptor, type I

Organism

Homo sapiens (human)

External Links

NCBI Gene

3554

HGNC

5993

PubChem

3554

Alliance of Genome Resources

HGNC:5993

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
Inflammatory response
NAD
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P14778	CD121 antigen-like family member A Interleukin-1 receptor alpha Interleukin-1 receptor type I p80
B8ZZW4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

« First

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1

2
GO Term	Evidence Code	PMID
response to interleukin-1	IDA	10383454
positive regulation of interleukin-1-mediated signaling pathway	IEA
cell surface receptor signaling pathway	TAS	1833184
regulation of inflammatory response	IBA
interleukin-1-mediated signaling pathway	IBA IDA	10383454 2950091

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-1-mediated signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interleukin-1

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of response to external stimulus [inference]

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-1-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
external side of plasma membrane	IEA
plasma membrane	IDA TAS	2530587
membrane	IDA	16477012

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 9 in total

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2

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	TAS	2530587
NAD+ nucleosidase activity	IEA
platelet-derived growth factor receptor binding	IPI	16477012
NAD+ nucleotidase, cyclic ADP-ribose generating	IEA
interleukin-1 binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

protein binding

signaling receptor binding [inference]

growth factor receptor binding [inference]

platelet-derived growth factor receptor binding

growth factor binding [inference]

interleukin-1 binding

enzyme binding [inference]

protease binding

cytokine binding [inference]

interleukin-1 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

cytokine receptor activity [inference]

interleukin-1 receptor activity

interleukin-1, type I, activating receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-1 receptor activity

interleukin-1, type I, activating receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:16301

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

Disease

Disease Ontology

Displaying entries **71 - 80** of **233** in total

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DO ID	Disease Name	Source
DOID:11432	endometriosis of ovary	DisGeNET
DOID:11612	polycystic ovary syndrome	DisGeNET
DOID:11714	gestational diabetes	DisGeNET
DOID:11716	prediabetes syndrome	DisGeNET
DOID:1184	nephrotic syndrome	DisGeNET
DOID:11870	Pick's disease	DisGeNET
DOID:11963	esophagitis	DisGeNET
DOID:1205	allergic disease	DisGeNET DisGeNET
DOID:12206	dengue hemorrhagic fever	DisGeNET
DOID:1222	cartilage disease	DisGeNET

The Human Phenotype Ontology

Displaying **all 6** entries
HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0001945	Fever
HP:0002653	Bone pain
HP:0002754	Osteomyelitis
HP:0003565	Elevated erythrocyte sedimentation rate
HP:0100847	Palmoplantar pustulosis