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interleukin 1 receptor type 1

Summary

Gene Symbol

IL1R1

Aliases

CD121A
D2S1473
interleukin-1 receptor, type I

Organism

Homo sapiens (human)

External Links

NCBI Gene

3554

HGNC

5993

PubChem

3554

Alliance of Genome Resources

HGNC:5993

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Disulfide bond
Glycoprotein
Hydrolase
Immunoglobulin domain
Inflammatory response
NAD
Phosphoprotein
Proteomics identification
Receptor
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P14778	CD121 antigen-like family member A Interleukin-1 receptor alpha Interleukin-1 receptor type I p80
B8ZZW4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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Last »
GO Term	Evidence Code	PMID
positive regulation of T-helper 1 cell cytokine production	IDA	10653850
immune response	TAS	9120302
positive regulation of type II interferon production	IDA	10653850
positive regulation of neutrophil extravasation	IEA
inflammatory response	IEA

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-1-mediated signaling pathway

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

immune response

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interleukin-1

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of immune effector process [inference]

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of leukocyte mediated immunity [inference]

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of lymphocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of immune effector process [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of leukocyte mediated immunity [inference]

positive regulation of lymphocyte mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of response to external stimulus [inference]

regulation of inflammatory response

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of immune response [inference]

regulation of adaptive immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of T cell mediated immunity [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of immune response [inference]

positive regulation of adaptive immune response [inference]

positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

positive regulation of T cell mediated immunity [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of T-helper 1 type immune response [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of response to cytokine stimulus [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of response to cytokine stimulus [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of inflammatory response

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

cytokine-mediated signaling pathway [inference]

interleukin-1-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of cytokine-mediated signaling pathway [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of interleukin-1-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

regulation of production of molecular mediator of immune response [inference]

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of cytokine-mediated signaling pathway [inference]

positive regulation of interleukin-1-mediated signaling pathway

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

positive regulation of production of molecular mediator of immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of cellular extravasation [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil migration [inference]

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of neutrophil extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of cellular extravasation [inference]

positive regulation of neutrophil extravasation

positive regulation of neutrophil migration [inference]

positive regulation of neutrophil extravasation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

regulation of cytokine production involved in immune response [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T cell cytokine production [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of T-helper 1 cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

regulation of type II interferon production [inference]

positive regulation of type II interferon production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production [inference]

positive regulation of cytokine production involved in immune response [inference]

positive regulation of T cell cytokine production [inference]

positive regulation of T-helper 1 cell cytokine production

positive regulation of type II interferon production

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
external side of plasma membrane	IEA
plasma membrane	IDA TAS	2530587
membrane	IDA	16477012

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane

plasma membrane

side of membrane [inference]

external side of plasma membrane

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	12925853 16286467 16477012
protease binding	IEA
interleukin-1, type I, activating receptor activity	IEA
interleukin-1 receptor activity	IBA IDA	10383454 2950091

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing N-glycosyl compounds [inference]

NAD+ nucleosidase activity

NAD+ nucleotidase, cyclic ADP-ribose generating

binding [inference]

protein binding

signaling receptor binding [inference]

growth factor receptor binding [inference]

platelet-derived growth factor receptor binding

growth factor binding [inference]

interleukin-1 binding

enzyme binding [inference]

protease binding

cytokine binding [inference]

interleukin-1 binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

cytokine receptor activity [inference]

interleukin-1 receptor activity

interleukin-1, type I, activating receptor activity

immune receptor activity [inference]

cytokine receptor activity [inference]

interleukin-1 receptor activity

interleukin-1, type I, activating receptor activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:16301

H₂O + NAD⁺

H⁺ + nicotinamide + ADP-D-ribose

Enzyme

PMID

Disease

Disease Ontology

Displaying entries **31 - 40** of **233** in total

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DO ID	Disease Name	Source
DOID:0110048	Alzheimer's disease 15	DisGeNET
DOID:0110115	autoimmune lymphoproliferative syndrome type 2A	DisGeNET
DOID:0110116	autoimmune lymphoproliferative syndrome type 2B	DisGeNET
DOID:0110119	autoimmune lymphoproliferative syndrome type 3	DisGeNET
DOID:0110741	type 1 diabetes mellitus 2	DisGeNET
DOID:0110742	type 1 diabetes mellitus 3	DisGeNET
DOID:0110743	type 1 diabetes mellitus 4	DisGeNET
DOID:0110744	type 1 diabetes mellitus 5	DisGeNET
DOID:0110745	type 1 diabetes mellitus 6	DisGeNET
DOID:0110746	type 1 diabetes mellitus 7	DisGeNET

The Human Phenotype Ontology

Displaying **all 6** entries
HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0001945	Fever
HP:0002653	Bone pain
HP:0002754	Osteomyelitis
HP:0003565	Elevated erythrocyte sedimentation rate
HP:0100847	Palmoplantar pustulosis

Displaying 1 entry
Disease ID	Disease Name
OMIM:259680	chronic recurrent multifocal osteomyelitis 3

PubChem Disease

MedGen Diseases

Chronic recurrent multifocal osteomyelitis 3

OMIM Phenotypes

CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS 3; CRMO3

KEGG Diseases

Chronic recurrent multifocal osteomyelitis

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **11 - 20** of 53 in total

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Species	Gene ID	Orthologous MAtrix
Macaca mulatta	711726	MACMU08638
Macaca nemestrina	105490126	MACNE13391
Papio anubis	101003909	PAPAN09600
Mandrillus leucophaeus	105531618	MANLE02031
Gorilla gorilla gorilla	101133600	GORGO25467
Pan paniscus	100972617	PANPA25413
Pan troglodytes	459460	PANTR28348
Canis lupus familiaris	481328	CANLF01744
Vulpes vulpes	112915144	VULVU06625
Ursus americanus	123775960	URSAM11340

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

PubChem Disease

International Collaboration

Acknowledgements