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NADH:ubiquinone oxidoreductase complex assembly factor 4

Summary

Gene Symbol

Ndufaf4

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

362495

PubChem

362495

Alliance of Genome Resources

RGD:735162

Annotation

Keyword

Calmodulin-binding
Membrane
Mitochondrion
Myristate
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6IIG9
Q9NQR8	Hormone-regulated proliferation-associated protein of 20 kDa homolog Protein HRPAP20

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	14871833
NADH dehydrogenase complex assembly	ISO
negative regulation of apoptotic process	IMP	14871833
defense response to virus	ISO
mitochondrial respiratory chain complex I assembly	IBA IEA ISO

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

NADH dehydrogenase complex assembly

mitochondrial respiratory chain complex I assembly

mitochondrial respiratory chain complex assembly [inference]

mitochondrial respiratory chain complex I assembly

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrial membrane	ISO
mitochondrion	IBA IEA ISO
cytosol	IEA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

organelle membrane [inference]

mitochondrial membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying 1 entry
GO Term	Evidence Code	PMID
calmodulin binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

calmodulin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

NADH dehydrogenase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying 1 entry
Gene Ontology
mitochondrial respiratory chain complex I assembly

Displaying 1 entry
InterPro
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0112077	nuclear type mitochondrial complex I deficiency 15	Alliance of Genome Resources

Ortholog

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	29078		HGNC:21034	HUMAN85804
Drosophila melanogaster	41227		FB:FBgn0037777
Mus musculus	68493	10090_1:0010fe	MGI:1915743	MOUSE42310
Caenorhabditis elegans	178039		WB:WBGene00007113
Canis lupus familiaris	475001			CANLF03002
Bos taurus	615440			BOVIN35659
Macaca mulatta	705102			MACMU35623
Pan troglodytes	735873			PANTR38722
Danio rerio	794169		ZFIN:ZDB-GENE-060810-114	DANRE19552
Equus caballus	100071449			HORSE01213

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Annotation

OrthoDB (Group)

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Acknowledgements