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MIRAGE
signal peptide peptidase-like 2B
Summary
- Gene Symbol
-
- Sppl2b
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell membrane
- Endosome
- Glycoprotein
- Golgi apparatus
- Hydrolase
- Lysosome
- Protease
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5PQL3 |
|
| A6K8E3 |
|
| A0A8L2R960 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis | ||
| membrane protein ectodomain proteolysis | ||
| membrane protein ectodomain proteolysis | ||
| membrane protein ectodomain proteolysis | ||
| membrane protein intracellular domain proteolysis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| nucleoplasm | ||
| nucleoplasm | ||
| lysosomal membrane | ||
| lysosomal membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| aspartic endopeptidase activity, intramembrane cleaving | ||
| aspartic endopeptidase activity, intramembrane cleaving | ||
| aspartic endopeptidase activity, intramembrane cleaving | ||
| aspartic endopeptidase activity, intramembrane cleaving | ||
| protein homodimerization activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- signal peptide peptidase-like
- Functional Category
-
- E: Amino acid transport and metabolism
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| aspartic endopeptidase activity, intramembrane cleaving |
| hydrolase activity |
| membrane protein proteolysis |
| InterPro |
|---|
| PA domain |
| Peptidase A22B, signal peptide peptidase |
| Presenilin/signal peptide peptidase |
