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Guidelines

MIRAGE

signaling receptor and transporter of retinol STRA6

Summary

Gene Symbol

Stra6

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

363071

PubChem

363071

Alliance of Genome Resources

RGD:1307551

Annotation

Keyword

Cell membrane
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Retinol-binding
Transmembrane helix
Transport
Vitamin A

Proteins

Displaying 1 entry
UniProt	Protein Name
Q4QR83	Retinol-binding protein receptor STRA6 Stimulated by retinoic acid gene 6 protein homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 68 in total

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GO Term	Evidence Code	PMID
blood vessel development	ISO
kidney development	ISO
kidney development	IEA
pulmonary valve morphogenesis	ISO
pulmonary valve morphogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

learning or memory [inference]

observational learning [inference]

imitative learning [inference]

vocal learning

learned vocalization behavior or vocal learning [inference]

vocal learning

neuromuscular process

behavior [inference]

learning or memory [inference]

observational learning [inference]

imitative learning [inference]

vocal learning

learned vocalization behavior or vocal learning [inference]

vocal learning

feeding behavior

mechanosensory behavior [inference]

auditory behavior [inference]

vocal learning

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

anatomical structure morphogenesis [inference]

heart valve morphogenesis [inference]

pulmonary valve morphogenesis

animal organ morphogenesis [inference]

uterus morphogenesis

sensory organ morphogenesis [inference]

nose morphogenesis

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis

digestive tract morphogenesis

anatomical structure formation involved in morphogenesis [inference]

embryonic camera-type eye formation

anatomical structure development [inference]

blood vessel development

cardiac septum development [inference]

ventricular septum development

tissue development [inference]

epithelium development [inference]

lung epithelium development [inference]

alveolar primary septum development

muscle tissue development [inference]

smooth muscle tissue development

tube development [inference]

digestive tract development [inference]

embryonic digestive tract development

paramesonephric duct development

lung alveolus development

animal organ development [inference]

kidney development

sensory organ development [inference]

eye development [inference]

camera-type eye development

ear development

heart development

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

lung development

embryonic organ development [inference]

embryonic digestive tract development

gland development [inference]

adrenal gland development

genitalia development [inference]

female genitalia development

reproductive structure development [inference]

genitalia development [inference]

female genitalia development

system development [inference]

vasculature development [inference]

lung vasculature development

muscle structure development [inference]

muscle organ development [inference]

skeletal muscle organ development [inference]

diaphragm development

growth [inference]

developmental growth

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to lipid [inference]

response to retinoic acid

response to oxygen-containing compound [inference]

response to retinoic acid

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

vitamin A transport [inference]

vitamin A import into cell

transmembrane transport [inference]

vitamin transmembrane transport [inference]

vitamin A import into cell

organic substance transport [inference]

lipid transport [inference]

isoprenoid transport [inference]

terpenoid transport [inference]

retinol transport

vitamin A transport [inference]

vitamin A import into cell

lipid import into cell [inference]

vitamin A import into cell

organic hydroxy compound transport [inference]

retinol transport

import into cell [inference]

vitamin A import into cell

establishment of localization in cell

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of multicellular organismal process [inference]

positive regulation of behavior

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of receptor signaling pathway via STAT [inference]

regulation of receptor signaling pathway via JAK-STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via JAK-STAT

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

positive regulation of behavior

positive regulation of multicellular organismal process [inference]

positive regulation of behavior

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
protein-containing complex	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
retinal binding	IEA
retinol binding	IEA
retinol transmembrane transporter activity	ISS
retinol transmembrane transporter activity	ISO
retinol transmembrane transporter activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

retinol transmembrane transporter activity

transmembrane transporter activity [inference]

vitamin transmembrane transporter activity [inference]

retinol transmembrane transporter activity

organic hydroxy compound transmembrane transporter activity [inference]

alcohol transmembrane transporter activity [inference]

retinol transmembrane transporter activity

binding [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

small molecule binding [inference]

vitamin binding [inference]

alcohol binding [inference]

retinol binding

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

STRA6

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms
V: Defense mechanisms

Displaying **all 5** entries
Gene Ontology
retinal binding
retinol binding
retinol transmembrane transporter activity
retinol transport
vitamin A import into cell

Displaying 1 entry
InterPro
Receptor for retinol uptake STRA6-like

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026