inositol polyphosphate phosphatase like 1
| UniProt | Protein Name |
|---|---|
| O15357 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylinositol 3-kinase/protein kinase B signal transduction | ||
| negative regulation of insulin-like growth factor receptor signaling pathway | ||
| phosphatidylinositol dephosphorylation | ||
| regulation of immune response | ||
| ERK1 and ERK2 cascade |
| GO Term | Evidence Code | PMID |
|---|---|---|
| spindle pole | ||
| nucleus | ||
| Golgi apparatus | ||
| cytosol | ||
| cytosol |
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| inositol-polyphosphate 5-phosphatase activity | ||
| protein binding | ||
| SH3 domain binding | ||
| phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity |
| InterPro |
|---|
| Endonuclease/exonuclease/phosphatase superfamily |
| Inositol polyphosphate-related phosphatase |
| SH2 domain superfamily |
| SH2 domain |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10763 | hypertension | |
| DOID:9352 | type 2 diabetes mellitus | |
| DOID:9970 | obesity |
| HPO ID | HPO Term |
|---|---|
| HP:0000774 | Narrow chest |
| HP:0000882 | Hypoplastic scapulae |
| HP:0000895 | Lateral clavicle hook |
| HP:0000907 | Anterior rib cupping |
| HP:0000922 | Posterior rib cupping |
| HP:0000944 | Abnormal metaphysis morphology |
| HP:0000946 | Hypoplastic ilia |
| HP:0000947 | Dumbbell-shaped long bone |
| HP:0000969 | Edema |
| HP:0001004 | Lymphedema |
| Disease ID | Disease Name |
|---|---|
| OMIM:258480 |
|
| ORPHA:3144 |
|
| ORPHA:2746 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3636 | Xenbase:XB-GENE-6487464 | ||
| 16332 | ZFIN:ZDB-GENE-030131-3904 | MOUSE56308 | |
| 65038 | ZFIN:ZDB-GENE-030131-3904 | RATNO17790 | |
| 451403 | PANTR03744 | ||
| 485209 | CANLF08305 | ||
| 718421 | MACMU10194 | ||
| 783833 | BOVIN07167 | ||
| 100066037 | HORSE38256 | ||
| 100222899 | TAEGU09778 | ||
| 100396447 | CALJA04607 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.4.0
Last updated: December 8, 2025