pancreatic and duodenal homeobox 1
| UniProt | Protein Name |
|---|---|
| P52945 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| liver development | ||
| type B pancreatic cell differentiation | ||
| type B pancreatic cell differentiation | ||
| type B pancreatic cell differentiation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| chromatin | ||
| nucleus | ||
| nucleoplasm | ||
| cytosol | ||
| nuclear speck |
| GO Term | Evidence Code | PMID |
|---|---|---|
| sequence-specific double-stranded DNA binding | ||
| promoter-specific chromatin binding |
| Gene Ontology |
|---|
| type B pancreatic cell differentiation |
| InterPro |
|---|
| Homeobox domain, metazoa |
| Homeobox domain |
| Homeobox, conserved site |
| Homeobox-like domain superfamily |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0061003 | pancreatic agenesis 1 | |
| DOID:0111103 | maturity-onset diabetes of the young type 4 | |
| DOID:3526 | cerebral infarction | |
| DOID:4195 | hyperglycemia | |
| DOID:9352 | type 2 diabetes mellitus |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025