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MIRAGE
Cathepsin L1

Summary
Gene Symbol
  • CtsL1
Organism
Drosophila melanogaster (fruit fly)
NCBI Gene
36546
PubChem
36546
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Developmental protein
  • Digestion
  • Disulfide bond
  • Glycoprotein
  • Lysosome
  • Proteomics identification
  • Reference proteome
  • Signal
  • Thiol protease
  • Zymogen
Proteins
Displaying all 2 entries
UniProt Protein Name
Q95029
  • Cysteine proteinase 1
A0A0B4JD48
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
proteolysis
proteolysis
proteolysis
immune response
digestion
GO Hierarchy
Displaying entries 1 - 5 of 6 in total
GO Term Evidence Code PMID
cysteine-type endopeptidase activity
cysteine-type endopeptidase activity
peptidase activity
cysteine-type peptidase activity
cysteine-type peptidase activity
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Cathepsin L
Functional Category
  • E: Amino acid transport and metabolism
  • M: Cell wall/membrane/envelope biogenesis
  • V: Defense mechanisms
Displaying all 7 entries
Gene Ontology
cysteine-type endopeptidase activator activity involved in apoptotic process
cysteine-type endopeptidase activity
hydrolase activity
immune response
positive regulation of apoptotic signaling pathway
proteolysis involved in protein catabolic process
proteolysis
Displaying all 8 entries
InterPro
Cathepsin propeptide inhibitor domain (I29)
Cysteine peptidase, asparagine active site
Cysteine peptidase, cysteine active site
Cysteine peptidase, histidine active site
Papain-like cysteine endopeptidase
Papain-like cysteine peptidase superfamily
Peptidase C1A, papain C-terminal
Peptidase C1A
Alliance of Genome Resources
Expression
Displaying all 5 entries
Location References
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:1574 alcohol use disorder
Ortholog
Displaying entries 1 - 10 of 18 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
1513 Xenbase:XB-GENE-986812
1514 Xenbase:XB-GENE-966214
1515 Xenbase:XB-GENE-966214
13038 Xenbase:XB-GENE-986812
13039 Xenbase:XB-GENE-966214
26898 ZFIN:ZDB-GENE-980526-285
29174 ZFIN:ZDB-GENE-980526-285
29175 Xenbase:XB-GENE-986812
36546 Xenbase:XB-GENE-986812
56092 ZFIN:ZDB-GENE-980526-285
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025