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carboxypeptidase N subunit 1

Summary

Gene Symbol

Cpn1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

365466

PubChem

365466

Alliance of Genome Resources

RGD:70931

Annotation

Keyword

Carboxypeptidase
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Secreted
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6JHE4
Q9EQV8	Carboxypeptidase N polypeptide 1 Carboxypeptidase N small subunit

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
bradykinin catabolic process	IMP	11299220
proteolysis	IEA
response to glucocorticoid	IDA	10485340
peptide metabolic process	IBA
protein catabolic process	IDA	11021404

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

protein metabolic process [inference]

proteolysis

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

protein metabolic process [inference]

proteolysis

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

peptide metabolic process

peptide catabolic process [inference]

bradykinin catabolic process

protein metabolic process [inference]

proteolysis

protein processing

protein catabolic process

protein maturation [inference]

protein processing

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process

peptide catabolic process [inference]

bradykinin catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process [inference]

bradykinin catabolic process

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

response to lipid [inference]

response to steroid hormone [inference]

response to corticosteroid [inference]

response to glucocorticoid

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IBA IDA	10485340

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying **all 3** entries
GO Term	Evidence Code	PMID
zinc ion binding	IEA
metallocarboxypeptidase activity	IBA IEA
carboxypeptidase activity	IDA IMP ISO	11021404 11299220

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity

metallocarboxypeptidase activity

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

metallopeptidase activity [inference]

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

exopeptidase activity [inference]

carboxypeptidase activity

metallocarboxypeptidase activity

metalloexopeptidase activity [inference]

metallocarboxypeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

carboxypeptidase N catalytic chain

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
carboxypeptidase activity
metallocarboxypeptidase activity
peptide metabolic process
proteolysis
zinc ion binding

Displaying **all 2** entries
InterPro
Carboxypeptidase-like, regulatory domain superfamily
Peptidase M14, carboxypeptidase A

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
extracellular space	PMID:10485340

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111583	carboxypeptidase N deficiency	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **111** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	1369		HGNC:2312	HUMAN02485
Mus musculus	93721	10090_1:0054d9	MGI:2135874	MOUSE26000
Caenorhabditis elegans	177940		WB:WBGene00001189
Caenorhabditis elegans	181684		WB:WBGene00012073
Danio rerio	337172		ZFIN:ZDB-GENE-030131-9116	DANRE03394
Canis lupus familiaris	477795			CANLF11383
Bos taurus	536753			BOVIN21344
Xenopus tropicalis	550020		Xenbase:XB-GENE-967670
Macaca mulatta	709434			MACMU45431
Monodelphis domestica	100020383			MONDO05420

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