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integrin subunit beta 1

Summary

Gene Symbol

ITGB1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3688

PubChem

3688

Alliance of Genome Resources

HGNC:6153

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Calcium
Cell adhesion
Cell junction
Cell membrane
Cell projection
Direct protein sequencing
Disulfide bond
EGF-like domain
Endosome
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Integrin
Isopeptide bond
Magnesium
Metal-binding
Myogenesis
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P05556	Fibronectin receptor subunit beta Glycoprotein IIa VLA-4 subunit beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 80 in total

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GO Term	Evidence Code	PMID
G1/S transition of mitotic cell cycle	IEA
establishment of mitotic spindle orientation	IMP	30992345
angiogenesis	IDA	29763414
in utero embryonic development	IEA
cell migration involved in sprouting angiogenesis	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

syncytium formation [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

cell adhesion

cell-substrate adhesion

cell-matrix adhesion

calcium-independent cell-matrix adhesion

cell adhesion mediated by integrin

cell-cell adhesion mediated by integrin

cell-cell adhesion

leukocyte cell-cell adhesion

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

cell population proliferation [inference]

neural precursor cell proliferation [inference]

neuroblast proliferation

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

cell cycle process [inference]

cell cycle phase transition [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

cell cycle G1/S phase transition [inference]

G1/S transition of mitotic cell cycle

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

mitotic cell cycle process [inference]

mitotic cell cycle phase transition [inference]

G1/S transition of mitotic cell cycle

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

cellular developmental process [inference]

cell fate specification [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

cardiocyte differentiation [inference]

cardioblast differentiation [inference]

cardiac muscle cell myoblast differentiation

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

myoblast differentiation

cardiac muscle cell myoblast differentiation

mesodermal cell differentiation

stem cell differentiation [inference]

cardioblast differentiation [inference]

cardiac muscle cell myoblast differentiation

cell motility [inference]

cell migration

ameboidal-type cell migration [inference]

epithelial cell migration [inference]

endothelial cell migration [inference]

blood vessel endothelial cell migration [inference]

cell migration involved in sprouting angiogenesis

germ cell migration

wound healing, spreading of cells [inference]

wound healing, spreading of epidermal cells

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

microtubule cytoskeleton organization involved in mitosis [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

cell projection organization

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

plasma membrane bounded cell projection organization [inference]

lamellipodium organization [inference]

lamellipodium assembly

plasma membrane bounded cell projection assembly [inference]

lamellipodium assembly

extracellular structure organization [inference]

extracellular matrix organization

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization

basement membrane organization

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

cell-cell fusion [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

B cell differentiation

B cell activation [inference]

B cell differentiation

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

visual behavior [inference]

visual learning

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of blood-brain barrier

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

formation of radial glial scaffolds

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

syncytium formation [inference]

syncytium formation by plasma membrane fusion [inference]

myoblast fusion

anatomical structure development [inference]

multicellular organism development [inference]

embryo development [inference]

embryo development ending in birth or egg hatching [inference]

chordate embryonic development [inference]

in utero embryonic development

animal organ development [inference]

muscle organ development

muscle structure development [inference]

muscle organ development

cellular developmental process [inference]

cell fate specification [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

cardiocyte differentiation [inference]

cardioblast differentiation [inference]

cardiac muscle cell myoblast differentiation

cardiac muscle cell differentiation

muscle cell differentiation [inference]

striated muscle cell differentiation [inference]

cardiac muscle cell differentiation

myoblast differentiation

cardiac muscle cell myoblast differentiation

mesodermal cell differentiation

stem cell differentiation [inference]

cardioblast differentiation [inference]

cardiac muscle cell myoblast differentiation

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension [inference]

axon extension

developmental growth involved in morphogenesis [inference]

neuron projection extension [inference]

axon extension

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

maintenance of blood-brain barrier

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

neuroinflammatory response [inference]

reactive gliosis

cellular defense response

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

response to endogenous stimulus [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to activity [inference]

response to muscle activity

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to lipoprotein particle [inference]

cellular response to low-density lipoprotein particle stimulus

cellular response to stimulus [inference]

cellular response to lipoprotein particle stimulus [inference]

cellular response to low-density lipoprotein particle stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor internalization

phagocytosis

establishment of localization in cell [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

organelle localization [inference]

spindle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

establishment of organelle localization [inference]

establishment of spindle localization [inference]

establishment of mitotic spindle localization [inference]

establishment of mitotic spindle orientation

establishment of spindle orientation [inference]

establishment of mitotic spindle orientation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of collagen catabolic process

regulation of collagen metabolic process [inference]

regulation of collagen catabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of spontaneous synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of organic acid transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transport [inference]

regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter uptake [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amine transport [inference]

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transport [inference]

regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

positive regulation of fibroblast migration

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to wounding [inference]

positive regulation of wound healing

positive regulation of transport [inference]

positive regulation of organic acid transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of neurotransmitter transport [inference]

positive regulation of neurotransmitter uptake [inference]

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amine transport [inference]

positive regulation of amino acid transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of amino acid uptake involved in synaptic transmission [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of anoikis

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of response to wounding [inference]

positive regulation of wound healing

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of response to stress [inference]

regulation of response to wounding [inference]

regulation of wound healing [inference]

positive regulation of wound healing

positive regulation of response to wounding [inference]

positive regulation of wound healing

regulation of cellular response to growth factor stimulus [inference]

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of cellular response to vascular endothelial growth factor stimulus [inference]

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

transforming growth factor beta receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of fibroblast growth factor receptor signaling pathway [inference]

positive regulation of fibroblast growth factor receptor signaling pathway

regulation of vascular endothelial growth factor signaling pathway [inference]

positive regulation of vascular endothelial growth factor signaling pathway

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of Rho protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of spontaneous synaptic transmission

regulation of transmembrane transport [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of monoatomic ion transmembrane transport [inference]

regulation of monoatomic cation transmembrane transport [inference]

regulation of potassium ion transmembrane transport [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

regulation of amino acid transmembrane transport [inference]

regulation of amino acid import across plasma membrane [inference]

regulation of L-glutamate import across plasma membrane [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of glutamate uptake involved in transmission of nerve impulse [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

positive regulation of apoptotic process

negative regulation of apoptotic process [inference]

negative regulation of anoikis

regulation of anoikis [inference]

negative regulation of anoikis

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of anoikis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neuron differentiation [inference]

negative regulation of neuron differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

positive regulation of transmembrane transport [inference]

positive regulation of L-glutamate import across plasma membrane [inference]

positive regulation of glutamate uptake involved in transmission of nerve impulse

positive regulation of programmed cell death [inference]

positive regulation of apoptotic process

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of small GTPase mediated signal transduction [inference]

negative regulation of Ras protein signal transduction [inference]

negative regulation of Rho protein signal transduction

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process [inference]

negative regulation of anoikis

negative regulation of cell differentiation [inference]

negative regulation of neuron differentiation

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse pruning

regulation of cell cycle

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of fibroblast migration [inference]

positive regulation of fibroblast migration

positive regulation of cell migration

positive regulation of fibroblast migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of fibroblast migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of blood circulation [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasoconstriction

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of tube size [inference]

regulation of tube diameter [inference]

blood vessel diameter maintenance [inference]

regulation of vasoconstriction [inference]

negative regulation of vasoconstriction

regulation of molecular function [inference]

regulation of transporter activity [inference]

regulation of transmembrane transporter activity [inference]

regulation of monoatomic ion transmembrane transporter activity [inference]

regulation of potassium ion transmembrane transporter activity [inference]

regulation of inward rectifier potassium channel activity

regulation of cation channel activity [inference]

regulation of inward rectifier potassium channel activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

regulation of hydrolase activity [inference]

regulation of GTPase activity [inference]

positive regulation of GTPase activity

positive regulation of hydrolase activity [inference]

positive regulation of GTPase activity

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GO Term	Evidence Code	PMID
ruffle	TAS	11919189
cytoplasm	IDA	16803572
plasma membrane	NAS	10455171
plasma membrane	TAS
plasma membrane	IDA	12869515 16803572 21310825

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical entity [inference]

membrane

plasma membrane

sarcolemma

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

bounding membrane of organelle [inference]

endosome membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse

neuromuscular junction

excitatory synapse [inference]

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

Schaffer collateral - CA1 synapse

glutamatergic synapse [inference]

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

neuron to neuron synapse [inference]

asymmetric synapse [inference]

asymmetric, glutamatergic, excitatory synapse [inference]

cerebellar climbing fiber to Purkinje cell synapse

anchoring junction [inference]

cell-cell junction [inference]

cell-cell contact zone [inference]

intercalated disc

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

myelin sheath abaxonal region

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

glial cell projection

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

pigment granule [inference]

melanosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear region of cytoplasm

side of membrane [inference]

external side of plasma membrane

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	PMID
magnesium ion binding	IDA	33962943
virus receptor activity	IEA
fibronectin binding	IDA	26763945
fibronectin binding	IBA
fibronectin binding	IPI	11792823

GO Hierarchy

molecular function

binding [inference]

protein binding

fibronectin binding

signaling receptor binding [inference]

integrin binding

integrin binding involved in cell-matrix adhesion

cytoskeletal protein binding [inference]

actin binding

enzyme binding [inference]

protease binding

kinase binding [inference]

protein kinase binding

protein tyrosine kinase binding

cytokine binding [inference]

chemokine binding [inference]

C-X3-C chemokine binding

laminin binding

protein dimerization activity [inference]

protein heterodimerization activity

cell adhesion molecule binding

integrin binding

integrin binding involved in cell-matrix adhesion

cadherin binding

cell adhesion mediator activity [inference]

cell-matrix adhesion mediator activity [inference]

exogenous protein binding [inference]

virus receptor activity

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

protein-containing complex binding

integrin binding

integrin binding involved in cell-matrix adhesion

collagen binding [inference]

collagen binding involved in cell-matrix adhesion

extracellular matrix binding [inference]

laminin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

coreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Integrin beta

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cell adhesion mediated by integrin
cell migration
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 5** entries
InterPro
Integrin beta subunit, VWA domain
Integrin beta subunit, tail
Integrin beta subunit
Integrin domain superfamily
von Willebrand factor A-like domain superfamily

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3688	Xenbase:XB-GENE-946725
Drosophila melanogaster	3689	FB:FBgn0004657
Drosophila melanogaster	3690	FB:FBgn0004657
Drosophila melanogaster	3693	FB:FBgn0004657
Drosophila melanogaster	3694	FB:FBgn0004657
Drosophila melanogaster	3695	FB:FBgn0004657
Mus musculus	16412	Xenbase:XB-GENE-946725	MOUSE60000
Drosophila melanogaster	16414	FB:FBgn0004657
Drosophila melanogaster	16416	FB:FBgn0004657
Drosophila melanogaster	16419	FB:FBgn0004657

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements