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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
keratin 5
Summary
- Gene Symbol
-
- Krt5
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Coiled coil
- Cytoplasm
- Intermediate filament
- Keratin
- Methylation
- Phosphoprotein
- Reference proteome
- Proteins
| UniProt | Protein Name |
|---|---|
| Q6P6Q2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| intermediate filament polymerization | ||
| regulation of cell migration | ||
| biological_process | ||
| regulation of protein localization | ||
| response to mechanical stimulus |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cornified envelope | ||
| keratin filament | ||
| plasma membrane | ||
| intermediate filament | ||
| cytoplasm |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| structural constituent of skin epidermis | ||
| scaffold protein binding |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- keratin, type II cytoskeletal 5
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intermediate filament organization |
| keratinization |
| structural constituent of skin epidermis |
| InterPro |
|---|
| Intermediate filament protein, conserved site |
| Intermediate filament, rod domain |
| Keratin type II head |
| Keratin, type II |
Alliance of Genome Resources
- Expression
| Location | References |
|---|---|
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060256 | Dowling-Degos disease | |
| DOID:0060735 | epidermolysis bullosa simplex Dowling-Meara type | |
| DOID:0111346 | epidermolysis bullosa simplex with mottled pigmentation | |
| DOID:11054 | urinary bladder cancer | |
| DOID:4644 | epidermolysis bullosa simplex |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 3852 | HGNC:6442 | HUMAN12839 | ||
| 110308 | 10090_1:0047ac | MGI:96702 | MOUSE16730 | |
| 173973 | WB:WBGene00002054 | |||
| 180414 | WB:WBGene00002056 | |||
| 281268 | BOVIN29120 | |||
| 779830 | Xenbase:XB-GENE-876246 | |||
| 794486 | ZFIN:ZDB-GENE-000607-83 | |||
| 797351 | ZFIN:ZDB-GENE-991110-23 | |||
| 100303605 | SHEEP14280 | |||
| 100352658 | RABIT10368 |
