GlyCosmos Portal

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GO Term	Evidence Code	PMID
inositol-3,4,6-trisphosphate 1-kinase activity	IEA
catalytic activity		8662638
inositol-1,3,4-trisphosphate 5-kinase activity	EXP IBA	11042108
hydrolase activity	IEA
inositol-1,3,4-trisphosphate 6-kinase activity	EXP IBA	11042108

GO Hierarchy

molecular function

catalytic activity

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

inositol tetrakisphosphate kinase activity [inference]

inositol trisphosphate kinase activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

inositol tetrakisphosphate kinase activity [inference]

inositol trisphosphate kinase activity [inference]

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000100605

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K00913

Name

inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134]

References

Rhea

RHEA:13253

ATP + 1D-myo-inositol 1,3,4-trisphosphate

H⁺ + ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate

Enzyme

2.7.1.159

PMID

RHEA:20940

ATP + 1D-myo-inositol 1,3,4-trisphosphate

H⁺ + ADP + 1D-myo-inositol 1,3,4,6-tetrakisphosphate

Enzyme

2.7.1.159

PMID

RHEA:12452

ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate

H⁺ + ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate

Enzyme

2.7.1.134

PMID

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:0060224	atrial fibrillation	DisGeNET
DOID:0060250	idiopathic scoliosis	DisGeNET
DOID:0060326	myelomeningocele	DisGeNET
DOID:0080016	spina bifida	DisGeNET
DOID:1089	tethered spinal cord syndrome	DisGeNET
DOID:11847	coronary thrombosis	DisGeNET
DOID:162	cancer	DisGeNET
DOID:1837	diabetic ketoacidosis	DisGeNET
DOID:1936	atherosclerosis	DisGeNET
DOID:2348	arteriosclerotic cardiovascular disease	DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP005569
Gene Name: inositol-tetrakisphosphate 1-kinase

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103185398		CALMI32121
Latimeria chalumnae	102351625		LATCH19993
Danio rerio	100148744	ZFIN:ZDB-GENE-131126-72	DANRE12539
Danio rerio	406290	ZFIN:ZDB-GENE-040426-1953
Astyanax mexicanus	103031945		ASTMX08488
Ictalurus punctatus	108270336		ICTPU35416
Esox lucius	105015588		ESOLU45167
Salmo trutta	115162264		SALTR56198
Salmo trutta	115172556		SALTR71649
Gadus morhua	115543985		GADMO48866

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements