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cadherin 5

Summary

Gene Symbol

CDH5

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 374068
PubChem: 374068

Annotation

Keyword

3D-structure
Calcium
Cell adhesion
Cell junction
Cell membrane
Cleavage on pair of basic residues
Glycoprotein
Metal-binding
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8AYD0	Vascular endothelial cadherin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
cell morphogenesis	IEA	30032202
cardiac epithelial to mesenchymal transition
adherens junction organization	IEA	30032202
cell-cell adhesion mediated by cadherin
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IEA	30032202

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion mediated by cadherin

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly

cell-cell junction organization [inference]

multicellular organismal process [inference]

multicellular organism development

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis

epithelial cell morphogenesis [inference]

endothelial cell morphogenesis

anatomical structure development [inference]

multicellular organism development

system development [inference]

vasculature development

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of establishment or maintenance of cell polarity [inference]

regulation of establishment of cell polarity

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	22301074
adherens junction	IEA	30032202
catenin complex	IEA	30032202
bicellular tight junction	IEA	30032202
cytoplasm

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

catenin complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

adherens junction

tight junction [inference]

bicellular tight junction

Displaying **all 4** entries
GO Term	Evidence Code	PMID
beta-catenin binding
protein phosphatase binding
calcium ion binding	IEA	22301074 30032202
cadherin binding	IEA	30032202

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

beta-catenin binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

cell adhesion molecule binding [inference]

cadherin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Cadherin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 2** entries
Gene Ontology
calcium ion binding
homophilic cell adhesion via plasma membrane adhesion molecules

Displaying **all 3** entries
InterPro
Cadherin conserved site
Cadherin-like superfamily
Cadherin-like

Ortholog

Displaying entries **1 - 10** of 14 in total

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Species	Gene ID	OrthoDB
Meleagris gallopavo	100544769	9103_1:0028ed
Anas platyrhynchos	101793216	8839_0:002634
Anser cygnoides	106033247	8845_0:001732
Coturnix japonica	107319340	93934_0:002497
Numida meleagris	110404331	8996_0:0022f8
Phasianus colchicus	116243964	9054_0:003d15
Aythya fuligula	116493951	219594_0:00246b
Oxyura jamaicensis	118172822	8884_0:002596
Cygnus atratus	118246375	8868_0:0022e0
Cygnus olor	121076436	8869_0:00248d