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polypeptide N-acetylgalactosaminyltransferase 18

Summary

Gene Symbol

GALNT18

Aliases

GALNT15
GalNAc-T18
MGC71806
polypeptide GalNAc transferase 18

Organism

Homo sapiens (human)

External Links

NCBI Gene

374378

GGDB ID

gg183

HGNC

30488

mRNA

NM_198516

map

11p15.3

Protein

NP_940918.2

OMIM

615136

KEGG Gene ID

hsa:374378

PubChem

374378

Alliance of Genome Resources

HGNC:30488

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lectin
Manganese
Metal-binding
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6P9A2	Polypeptide GalNAc transferase 18 Polypeptide GalNAc transferase-like protein 4 Polypeptide N-acetylgalactosaminyltransferase-like protein 4 Protein-UDP acetylgalactosaminyltransferase-like protein 4 UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4
Q58A54	Protein-UDP acetylgalactosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA IDA	22186971

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cellular_component	ND
Golgi apparatus	IBA
Golgi membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
carbohydrate binding	IEA
polypeptide N-acetylgalactosaminyltransferase activity	IBA IDA	22186971

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

polypeptide N-acetylgalactosaminyltransferase activity

catalytic activity, acting on a protein [inference]

polypeptide N-acetylgalactosaminyltransferase activity

binding [inference]

carbohydrate binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000110328

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlycoGene Database (GGDB)

GGDB ID

gg183

Gene Symbol

GALNT18

KEGG BRITE Database

Orthology

K00710

Name

polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41]

References

9295285

Rhea

RHEA:23956

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

RHEA:52424

UDP-N-acetyl-α-D-galactosamine

H⁺ + UDP

Enzyme

2.4.1.41

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:3717	gastric adenocarcinoma	DisGeNET
DOID:7148	rheumatoid arthritis	DisGeNET

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Callorhinchus milii	103175071		CALMI06227
Danio rerio	100310831	ZFIN:ZDB-GENE-091014-1	DANRE40637
Danio rerio	100170813	ZFIN:ZDB-GENE-080723-30
Astyanax mexicanus	103042300		ASTMX09007
Electrophorus electricus	113578396		ELEEL02193
Esox lucius	105016932		ESOLU05555
Salmo trutta	115167295		SALTR83631
Salmo trutta	115203052		SALTR78287
Gadus morhua	115558237		GADMO11869
Poecilia reticulata	103462472		POERE24101

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Tools

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Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

International Collaboration

Acknowledgements