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potassium inwardly rectifying channel subfamily J member 1

Summary

Gene Symbol

KCNJ1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3758

PubChem

3758

Alliance of Genome Resources

HGNC:6255

JoGo

KCNJ1

TogoVar

KCNJ1

Annotation

Keyword

ATP-binding
Alternative splicing
Bartter syndrome
Cell membrane
Disease variant
Glycoprotein
Phosphoprotein
Potassium transport
Proteomics identification
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K432
P48048	ATP-regulated potassium channel ROM-K Inward rectifier K(+) channel Kir1.1 Potassium channel, inwardly rectifying subfamily J member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of monoatomic ion transmembrane transport	IBA
regulation of ion transmembrane transport	IBA
potassium ion import across plasma membrane	ISS
potassium ion import across plasma membrane	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport [inference]

potassium ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

potassium ion import across plasma membrane

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

regulation of monoatomic ion transport [inference]

regulation of ion transmembrane transport

regulation of cellular process [inference]

regulation of transmembrane transport [inference]

regulation of ion transmembrane transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	16357011
plasma membrane	IBA
monoatomic ion channel complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
inward rectifier potassium channel activity	ISS
inward rectifier potassium channel activity	IDA	7929082
potassium channel activity	IDA	16357011
ATP binding	ISS
phosphatidylinositol-4,5-bisphosphate binding	IDA	12086641

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

ligand-gated channel activity [inference]

ligand-gated monoatomic ion channel activity [inference]

ligand-gated monoatomic cation channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity

voltage-gated potassium channel activity [inference]

inward rectifier potassium channel activity

ATP-activated inward rectifier potassium channel activity

binding [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATP-sensitive inward rectifier potassium channel 1

Functional Category

G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
ATP-activated inward rectifier potassium channel activity
inward rectifier potassium channel activity
monoatomic ion transport
regulation of monoatomic ion transmembrane transport

Displaying **all 5** entries
InterPro
Immunoglobulin E-set
Inward rectifier potassium channel, C-terminal
Potassium channel, inwardly rectifying, Kir, cytoplasmic
Potassium channel, inwardly rectifying, Kir
Potassium channel, inwardly rectifying, transmembrane domain