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MIRAGE
potassium calcium-activated channel subfamily M alpha 1
Summary
- Gene Symbol
-
- KCNMA1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Disease variant
- Epilepsy
- Magnesium
- Metal-binding
- Palmitate
- Phosphoprotein
- Potassium channel
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Voltage-gated channel
- Proteins
| UniProt | Protein Name |
|---|---|
| D5MRH1 |
|
| A0A1W2PP94 |
|
| A0A1W2PQK5 |
|
| A0A087WZL8 |
|
| A0A1W2PR62 |
|
| S4R453 |
|
| Q12791 |
|
| A0A1W2PR56 |
|
| Q5SVJ7 |
|
| A0A1W2PPY5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| potassium ion transport | ||
| response to osmotic stress | ||
| intracellular potassium ion homeostasis | ||
| response to carbon monoxide |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| voltage-gated potassium channel activity | ||
| voltage-gated potassium channel activity | ||
| protein binding | ||
| calcium-activated potassium channel activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- calcium-activated potassium channel
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| monoatomic ion channel activity |
| monoatomic ion transport |
| potassium channel activity |
| InterPro |
|---|
| Calcium-activated potassium channel BK, alpha subunit |
| Calcium-activated potassium channel slowpoke-like |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0070442 | paroxysmal nonkinesigenic dyskinesia 3 | |
| DOID:10652 | Alzheimer's disease | |
| DOID:1827 | generalized epilepsy |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3778 | Xenbase:XB-GENE-922336 | ||
| 16531 | Xenbase:XB-GENE-922336 | MOUSE14594 | |
| 83731 | RATNO10584 | ||
| 157855 | FB:FBgn0003429 | ||
| 466115 | PANTR00967 | ||
| 574103 | MACMU45337 | ||
| 100008745 | RABIT06670 | ||
| 100064366 | HORSE18101 | ||
| 100227091 | TAEGU27397 | ||
| 100402638 | CALJA06634 |
