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kinesin family member 5B

Summary

Gene Symbol

KIF5B

Organism

Homo sapiens (human)

External Links

NCBI Gene

3799

PubChem

3799

Alliance of Genome Resources

HGNC:6324

JoGo

KIF5B

TogoVar

KIF5B

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Coiled coil
Cytoskeleton
Isopeptide bond
Lysosome
Membrane
Methylation
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
V9HW29
P33176	Conventional kinesin heavy chain Ubiquitous kinesin heavy chain
Q6P164

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **11 - 15** of 23 in total

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GO Term	Evidence Code	PMID
vesicle transport along microtubule	IDA	28426968
mitochondrion transport along microtubule	IEA
synaptic vesicle transport	IBA
centrosome localization	IMP	20386726
cellular response to type II interferon	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

natural killer cell mediated cytotoxicity

lymphocyte mediated immunity [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

immune response [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

cellular process [inference]

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

natural killer cell mediated cytotoxicity

microtubule-based process [inference]

microtubule-based movement

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

synaptic vesicle transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrion distribution [inference]

mitocytosis

organelle disassembly [inference]

stress granule disassembly

cytoplasm organization

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

organelle disassembly [inference]

stress granule disassembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

protein-RNA complex organization [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

export from cell [inference]

migracytosis [inference]

mitocytosis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

immune response [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

localization [inference]

protein-containing complex localization [inference]

receptor localization to synapse [inference]

anterograde dendritic transport of neurotransmitter receptor complex

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

synaptic vesicle transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

export from cell [inference]

migracytosis [inference]

mitocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

organelle localization [inference]

mitochondrion localization [inference]

mitochondrion distribution [inference]

mitocytosis

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

synaptic vesicle localization [inference]

synaptic vesicle transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

vacuolar localization [inference]

lysosome localization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

microtubule organizing center localization [inference]

centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of modification of synapse structure, modulating synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

positive regulation of potassium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of modification of synapse structure, modulating synaptic transmission

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of modification of synaptic structure [inference]

regulation of modification of synapse structure, modulating synaptic transmission

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of biological quality [inference]

regulation of membrane potential

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
mitochondrion	IEA
cytosol	TAS
cytosol	IDA
kinesin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

cytosol

cytosolic region [inference]

postsynaptic cytosol

membrane

organelle membrane [inference]

nuclear membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

cytolytic granule membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

perinuclear region of cytoplasm

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	ISS
microtubule motor activity	IDA	28426968
protein binding	IPI	15161933 19164528 20562859 21915095 25855459 28426968 28514442 32296183 33961781 35271311 36931259
ATP binding	IEA
microtubule binding	ISS