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kinesin family member 5B

Summary

Gene Symbol

KIF5B

Organism

Homo sapiens (human)

External Links

NCBI Gene

3799

PubChem

3799

Alliance of Genome Resources

HGNC:6324

JoGo

KIF5B

TogoVar

KIF5B

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Coiled coil
Cytoskeleton
Isopeptide bond
Lysosome
Membrane
Methylation
Microtubule
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
V9HW29
P33176	Conventional kinesin heavy chain Ubiquitous kinesin heavy chain
Q6P164

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 23 in total

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GO Term	Evidence Code	PMID
microtubule-based movement	TAS	7514426
cytoplasm organization	IEA
axon guidance	IBA
positive regulation of synaptic transmission, GABAergic	IEA
lysosome localization	IMP	22172677

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

leukocyte mediated cytotoxicity [inference]

natural killer cell mediated cytotoxicity

lymphocyte mediated immunity [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

immune response [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

cellular process [inference]

cell killing [inference]

leukocyte mediated cytotoxicity [inference]

natural killer cell mediated cytotoxicity

microtubule-based process [inference]

microtubule-based movement

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

synaptic vesicle transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

microtubule organizing center localization [inference]

centrosome localization

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

mitochondrion distribution [inference]

mitocytosis

organelle disassembly [inference]

stress granule disassembly

cytoplasm organization

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

organelle disassembly [inference]

stress granule disassembly

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

protein-RNA complex organization [inference]

protein-RNA complex disassembly [inference]

stress granule disassembly

export from cell [inference]

migracytosis [inference]

mitocytosis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

immune response [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

natural killer cell mediated immunity [inference]

natural killer cell mediated cytotoxicity

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to type II interferon [inference]

cellular response to type II interferon

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to type II interferon

localization [inference]

protein-containing complex localization [inference]

receptor localization to synapse [inference]

anterograde dendritic transport of neurotransmitter receptor complex

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

synaptic vesicle transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

export from cell [inference]

migracytosis [inference]

mitocytosis

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

organelle localization [inference]

mitochondrion localization [inference]

mitochondrion distribution [inference]

mitocytosis

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

synaptic vesicle localization [inference]

synaptic vesicle transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

synaptic vesicle transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

establishment of mitochondrion localization [inference]

establishment of mitochondrion localization, microtubule-mediated [inference]

mitochondrion transport along microtubule

mitocytosis

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

vacuolar localization [inference]

lysosome localization

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport [inference]

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport [inference]

retrograde axonal transport [inference]

retrograde neuronal dense core vesicle transport

dendritic transport [inference]

anterograde dendritic transport [inference]

anterograde dendritic transport of neurotransmitter receptor complex

axo-dendritic protein transport [inference]

anterograde axonal protein transport

organelle transport along microtubule [inference]

vesicle transport along microtubule

mitochondrion transport along microtubule

plus-end-directed organelle transport along microtubule [inference]

plus-end-directed vesicle transport along microtubule

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

vesicle cytoskeletal trafficking [inference]

vesicle transport along microtubule

dense core granule cytoskeletal transport [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

microtubule-based protein transport [inference]

protein transport along microtubule [inference]

axo-dendritic protein transport [inference]

anterograde axonal protein transport

protein localization to cell junction [inference]

protein localization to synapse [inference]

protein localization to presynapse [inference]

anterograde axonal protein transport

microtubule organizing center localization [inference]

centrosome localization

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of modification of synapse structure, modulating synaptic transmission

regulation of localization [inference]

regulation of transport [inference]

regulation of monoatomic ion transport [inference]

regulation of metal ion transport [inference]

regulation of potassium ion transport [inference]

positive regulation of potassium ion transport

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of transport [inference]

positive regulation of monoatomic ion transport [inference]

positive regulation of potassium ion transport

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic transmission, GABAergic [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

regulation of modification of synapse structure, modulating synaptic transmission

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of synaptic transmission, GABAergic

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of modification of synaptic structure [inference]

regulation of modification of synapse structure, modulating synaptic transmission

regulation of cellular localization [inference]

regulation of protein localization [inference]

positive regulation of protein localization [inference]

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to cell periphery [inference]

positive regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

positive regulation of protein localization to plasma membrane

positive regulation of protein localization to membrane [inference]

positive regulation of protein localization to plasma membrane

regulation of biological quality [inference]

regulation of membrane potential

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
mitochondrion	IEA
cytosol	TAS
cytosol	IDA
kinesin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

cytosol

cytosolic region [inference]

postsynaptic cytosol

membrane

organelle membrane [inference]

nuclear membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

cytolytic granule membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endocytic vesicle [inference]

phagocytic vesicle

perinuclear region of cytoplasm

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying entries **6 - 10** of 12 in total

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GO Term	Evidence Code	PMID
microtubule binding	IDA	28426968
microtubule binding	IBA
plus-end-directed microtubule motor activity	IBA
ATP hydrolysis activity	IBA
identical protein binding	IPI	17013387 18004302