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dynein regulatory complex subunit 1

Summary

Gene Symbol

Drc1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

381738

PubChem

381738

Alliance of Genome Resources

MGI:2685906

Annotation

Keyword

Coiled coil
Cytoskeleton
Flagellum
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3USS3	Coiled-coil domain-containing protein 164

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
regulation of cilium movement	IBA
single fertilization	IMP	34169321
determination of left/right symmetry	IMP	25807483
heart development	IMP	25807483
flagellated sperm motility	IMP	34169321

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

microtubule bundle formation [inference]

axoneme assembly

microtubule-based movement [inference]

cilium movement [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

cilium movement involved in cell motility [inference]

flagellated sperm motility

cellular process involved in reproduction in multicellular organism [inference]

sperm flagellum assembly

cell motility [inference]

cilium or flagellum-dependent cell motility [inference]

cilium-dependent cell motility

flagellated sperm motility

sperm motility [inference]

flagellated sperm motility

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

microtubule bundle formation [inference]

axoneme assembly

cilium organization

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

cellular component assembly [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

axoneme assembly

protein-containing complex assembly

axonemal dynein complex assembly

organelle assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

cell projection organization [inference]

cell projection assembly [inference]

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

plasma membrane bounded cell projection organization [inference]

cilium organization

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

plasma membrane bounded cell projection assembly [inference]

cilium assembly [inference]

motile cilium assembly [inference]

sperm flagellum assembly

protein-containing complex organization [inference]

protein-containing complex assembly

axonemal dynein complex assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

sperm flagellum assembly

fertilization [inference]

single fertilization

cellular process involved in reproduction in multicellular organism [inference]

sperm flagellum assembly

sperm motility [inference]

flagellated sperm motility

multicellular organismal process [inference]

system process [inference]

respiratory system process [inference]

mucociliary clearance

pattern specification process [inference]

specification of symmetry [inference]

determination of bilateral symmetry [inference]

determination of left/right symmetry

developmental process [inference]

developmental process involved in reproduction [inference]

sperm flagellum assembly

anatomical structure development [inference]

animal organ development [inference]

heart development

localization [inference]

establishment of localization [inference]

transport [inference]

extracellular transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

microtubule-based transport [inference]

epithelial cilium movement involved in extracellular fluid movement [inference]

mucociliary clearance

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process [inference]

regulation of microtubule-based movement [inference]

regulation of cilium movement

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytosol	IDA	27914912
axonemal dynein complex	IEA
cilium	IMP	34169321
axoneme	ISS
axoneme	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

dynein complex [inference]

axonemal dynein complex

catalytic complex [inference]

dynein complex [inference]

axonemal dynein complex

cellular anatomical entity [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

organelle [inference]

membrane-bounded organelle [inference]

cilium

motile cilium [inference]

9+2 motile cilium [inference]

sperm flagellum

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Dynein regulatory complex protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
axonemal dynein complex assembly

Displaying **all 3** entries
InterPro
Dynein regulatory complex protein 1, C-terminal
Dynein regulatory complex protein 1/2, N-terminal
Dynein regulatory complex protein

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050144	Kartagener syndrome	Alliance of Genome Resources
DOID:0050545	visceral heterotaxy	Alliance of Genome Resources
DOID:0110596	primary ciliary dyskinesia 21	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 61 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	92749	Xenbase:XB-GENE-5967064	HUMAN61841
Rattus norvegicus	362712		RATNO35413
Xenopus tropicalis	381738	Xenbase:XB-GENE-5967064
Pan troglodytes	459082		PANTR27221
Canis lupus familiaris	475690		CANLF04958
Bos taurus	509524		BOVIN02827
Monodelphis domestica	100030821		MONDO09098
Danio rerio	100034551		DANRE18884
Ornithorhynchus anatinus	100078391		ORNAN26919
Pongo abelii	100450913		PONAB23248

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OrthoDB (Group)

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Acknowledgements