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cyclin dependent kinase like 5

Summary

Gene Symbol

Cdkl5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

382253

PubChem

382253

Alliance of Genome Resources

MGI:1278336

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Cytoskeleton
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3UTQ8
A0A0G2JGW6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
neuron migration	ISO
protein localization to nucleus	IMP	27466189
positive regulation of axon extension	ISO
positive regulation of axon extension	IBA
protein autophosphorylation	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

protein autophosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation [inference]

protein autophosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation [inference]

protein autophosphorylation

cell motility [inference]

cell migration [inference]

neuron migration

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of biological process [inference]

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of dendritic spine development

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of axonogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of developmental growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

positive regulation of developmental growth [inference]

positive regulation of axon extension

regulation of dendrite development

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of developmental growth [inference]

positive regulation of axon extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of dendritic spine development

regulation of dendritic spine development [inference]

positive regulation of dendritic spine development

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of cellular component biogenesis [inference]

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of organelle assembly [inference]

regulation of cilium assembly

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of cellular process [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of axon extension

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

positive regulation of axon extension

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cell projection assembly [inference]

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

regulation of dendrite development

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of plasma membrane bounded cell projection assembly [inference]

regulation of cilium assembly

regulation of organelle organization [inference]

regulation of organelle assembly [inference]

regulation of cilium assembly

regulation of synapse organization [inference]

regulation of postsynapse organization

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of cell cycle

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis [inference]

positive regulation of axon extension

positive regulation of dendrite morphogenesis

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IBA
nucleus	IEA
nucleoplasm	ISO
cytoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

nucleoplasm

cytoplasm

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

dendrite cytoplasm

microtubule organizing center [inference]

membrane [inference]

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

site of polarized growth [inference]

growth cone [inference]

dendritic growth cone

leading edge membrane [inference]

ruffle membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

dendrite terminus [inference]

dendritic growth cone

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
protein kinase activity	ISO	27466189
protein kinase activity	IBA
cyclin-dependent protein serine/threonine kinase activity	IEA
ATP binding	ISO
ATP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity

protein kinase activity

protein serine/threonine kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

cyclin-dependent protein kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

cyclin-dependent protein kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

cyclin-dependent protein kinase activity [inference]

cyclin-dependent protein serine/threonine kinase activity

protein serine kinase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080467	developmental and epileptic encephalopathy 2	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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External Links

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Acknowledgements