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kinesin family member 11

Summary

Gene Symbol

KIF11

Organism

Homo sapiens (human)

External Links

NCBI Gene

3832

PubChem

3832

Alliance of Genome Resources

HGNC:6388

JoGo

KIF11

TogoVar

KIF11

Annotation

Keyword

3D-structure
ATP-binding
Acetylation
Coiled coil
Cytoskeleton
Disease variant
Isopeptide bond
Microtubule
Mitosis
Motor protein
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P52732	Kinesin-like protein 1 Kinesin-like spindle protein HKSP Kinesin-related motor protein Eg5 Thyroid receptor-interacting protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
mitotic cell cycle	TAS	8548803
microtubule-based movement	IEA
spindle organization	IMP	14718566
mitotic spindle organization	TAS	8548803
mitotic centrosome separation	IEA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

cell cycle [inference]

mitotic cell cycle

cell cycle process [inference]

spindle organization

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

spindle elongation

centrosome separation [inference]

mitotic centrosome separation

mitotic cell cycle process [inference]

mitotic centrosome separation

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

cell division

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization

mitotic spindle organization

mitotic spindle assembly

spindle assembly [inference]

mitotic spindle assembly

microtubule cytoskeleton organization involved in mitosis [inference]

mitotic spindle organization

mitotic spindle assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly [inference]

mitotic spindle assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of mitotic centrosome separation

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
spindle pole	IDA	14718566
nucleus	IBA
spindle	IDA	19001501
cytosol	TAS
cytosol	IDA

GO Hierarchy

cellular component

protein-containing complex

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

spindle pole

microtubule organizing center [inference]

ciliary basal body

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle

nucleus

intracellular non-membrane-bounded organelle [inference]

spindle

mitotic spindle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

spindle microtubule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
microtubule motor activity	TAS	8548803
protein binding	IPI	21303978 28169274
ATP binding	IEA
microtubule binding	IEA
plus-end-directed microtubule motor activity	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

plus-end-directed microtubule motor activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

plus-end-directed microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Kinesin

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding
plus-end-directed microtubule motor activity

Displaying **all 6** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein KIF11-like, kinesin motor domain
Kinesin-like protein KIF11-like
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060349	microcephaly with or without chorioretinopathy, lymphedema, or mental retardation	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements