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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
ADAM metallopeptidase domain 22 L homeolog
Summary
- Gene Symbol
-
- adam22.L
- Organism
- Xenopus laevis (African clawed frog)
Annotation
- Keyword
-
- Cell membrane
- Cleavage on pair of basic residues
- Disulfide bond
- EGF-like domain
- Glycoprotein
- Metalloprotease
- Reference proteome
- Signal
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8J0VH95 |
|
| A0A8J0VED6 |
|
| O42596 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity | ||
| metallopeptidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Disintegrin
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| InterPro |
|---|
| ADAM, cysteine-rich domain |
| Disintegrin domain superfamily |
| Disintegrin domain |
| Metallopeptidase, catalytic domain superfamily |
| Peptidase M12B, ADAM/reprolysin |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080434 | developmental and epileptic encephalopathy 61 |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 53616 | 9606_0:0014ba | HGNC:201 | ||
| 420537 | 9031_0:0009e8 | |||
| 482286 | 9615_0:00313d | |||
| 523645 | 9913_0:000da6 | |||
| 705350 | 9544_0:000f80 | |||
| 100027437 | 13616_0:003a5e | |||
| 100050380 | 9796_0:000f6b | |||
| 100088628 | 9258_0:002985 | |||
| 100220980 | 59729_0:000c10 | |||
| 100338906 | 9986_0:001cd4 |
