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microsomal signal peptidase 18 kDa subunit

Summary

Gene Symbol

NCU04519

Organism

Neurospora crassa OR74A

External Links

NCBI Gene: 3873068
PubChem: 3873068

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Protease
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7RY44	Signal peptidase I

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signal peptide processing	IEA	22301074 30032202
protein targeting to ER

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

signal peptide processing

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

signal peptide processing

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signal peptide processing

protein maturation [inference]

protein processing [inference]

signal peptide processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signal peptide processing

protein maturation [inference]

protein processing [inference]

signal peptide processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signal peptide processing

protein maturation [inference]

protein processing [inference]

signal peptide processing

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

signal peptide processing

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

signal peptide processing

protein maturation [inference]

protein processing [inference]

signal peptide processing

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of localization [inference]

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to endoplasmic reticulum [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to ER

establishment of protein localization to organelle [inference]

establishment of protein localization to endoplasmic reticulum [inference]

protein targeting to ER

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signal peptidase complex	IEA	30032202
membrane	IEA	22301074 30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

signal peptidase complex

endoplasmic reticulum protein-containing complex [inference]

signal peptidase complex

catalytic complex [inference]

peptidase complex [inference]

signal peptidase complex

cellular anatomical entity [inference]

membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase activity	IEA	22301074
peptidase activity

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Peptidase

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
hydrolase activity
proteolysis
serine-type endopeptidase activity
signal peptide processing

Displaying **all 5** entries
InterPro
LexA/Signal peptidase-like superfamily
Peptidase S24/S26A/S26B/S26C
Peptidase S26
Peptidase S26A, signal peptidase I, serine active site
Peptidase S26B

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Last updated: April 7, 2025

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