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autophagy protein Apg12

Summary

Gene Symbol

NCU10049

Organism

Neurospora crassa OR74A

External Links

NCBI Gene: 3874103
PubChem: 3874103

Annotation

Keyword

Autophagy
Isopeptide bond
Membrane
Protein transport
Reference proteome
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7S083	Autophagy-related protein 12

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	IEA	22301074 30032202
autophagy of mitochondrion	IEA	30032202
C-terminal protein lipidation	IEA	30032202
protein transport
piecemeal microautophagy of the nucleus

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

macromolecule modification [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein lipidation [inference]

C-terminal protein lipidation

post-translational protein modification [inference]

C-terminal protein amino acid modification [inference]

C-terminal protein lipidation

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

process utilizing autophagic mechanism [inference]

autophagy [inference]

autophagy of mitochondrion

macroautophagy [inference]

nucleophagy

piecemeal microautophagy of the nucleus

glycophagy

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization [inference]

autophagy of mitochondrion

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

organelle disassembly [inference]

autophagy of mitochondrion

cellular component disassembly [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

organelle disassembly [inference]

autophagy of mitochondrion

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

protein-containing complex organization [inference]

protein-containing complex disassembly [inference]

autophagosome maturation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

Displaying **all 4** entries
GO Term	Evidence Code	PMID
autophagosome membrane
cytoplasm	IEA	22301074 30032202
phagophore assembly site membrane	IEA	30032202
Atg12-Atg5-Atg16 complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

catalytic complex [inference]

transferase complex [inference]

Atg12-Atg5-Atg16 complex

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

autophagosome membrane

phagophore assembly site membrane

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Ubiquitin-like protein

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
autophagosome assembly
nucleophagy

Displaying **all 2** entries
InterPro
Ubiquitin-like domain superfamily
Ubiquitin-like protein Atg12

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025

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