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Submissions

leucine-1

Summary

Gene Symbol

leu-1

Organism

Neurospora crassa OR74A

External Links

NCBI Gene: 3879238
PubChem: 3879238

Annotation

Keyword

Cytoplasm
Leucine biosynthesis
Magnesium
Manganese
Metal-binding
NAD
Oxidoreductase
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P34738	Beta-IPM dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
glyoxylate cycle
amino acid biosynthetic process
leucine biosynthetic process	IEA	22301074 30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

glyoxylate cycle

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

organonitrogen compound biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

organic acid metabolic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

alpha-amino acid metabolic process [inference]

leucine metabolic process [inference]

leucine biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

monocarboxylic acid metabolic process [inference]

glyoxylate metabolic process [inference]

glyoxylate cycle

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

carboxylic acid biosynthetic process [inference]

amino acid biosynthetic process

alpha-amino acid biosynthetic process [inference]

leucine biosynthetic process

branched-chain amino acid biosynthetic process [inference]

leucine biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
cytosol	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

Displaying **all 3** entries
GO Term	Evidence Code	PMID
3-isopropylmalate dehydrogenase activity	IEA	22301074 30032202
magnesium ion binding	IEA	22301074
NAD binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

3-isopropylmalate dehydrogenase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Acknowledgements