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fear-of-intimacy

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

38976

PubChem

38976

Alliance of Genome Resources

FB:FBgn0024236

Annotation

Keyword

Cell membrane
Developmental protein
Differentiation
Glycoprotein
Neurogenesis
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix
Zinc transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
M9PES6
Q9VSL7	Protein fear-of-intimacy Protein kastchen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
zinc ion transport	IMP	15509557 16481356
intracellular zinc ion homeostasis	IMP	37069617
central nervous system development	IMP	10328928
gonadal mesoderm development	IMP	12702650 12900457 9435287
germ cell migration	TAS	9637912

GO Hierarchy

biological process

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

cellular developmental process [inference]

cell differentiation

cell motility [inference]

cell migration

germ cell migration

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development

cellular process involved in reproduction in multicellular organism [inference]

germ cell migration

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gonad morphogenesis

tube morphogenesis [inference]

tube fusion [inference]

branch fusion, open tracheal system

anatomical structure development [inference]

tissue development [inference]

mesoderm development [inference]

gonadal mesoderm development

mesenchyme development [inference]

gonadal mesoderm development

animal organ development [inference]

gonad development

reproductive structure development [inference]

gonad development

system development [inference]

central nervous system development

cellular developmental process [inference]

cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular zinc ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular zinc ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular zinc ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis

intracellular zinc ion homeostasis

inorganic ion homeostasis [inference]

intracellular zinc ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport

transition metal ion transport [inference]

zinc ion transport

zinc ion transmembrane transport

zinc ion import across plasma membrane

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

zinc ion transmembrane transport

zinc ion import across plasma membrane

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

zinc ion import across plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	12702650 15464587
plasma membrane	IBA
cell surface	IDA	12702650 16481356
membrane	IEA
basolateral plasma membrane	IDA	23322169

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
zinc ion transmembrane transporter activity	IDA	15509557
zinc ion transmembrane transporter activity	IMP	37069617
zinc ion transmembrane transporter activity	IBA
metal ion transmembrane transporter activity	IEA
monoatomic cation:bicarbonate symporter activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity

transition metal ion transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

monoatomic cation:bicarbonate symporter activity

salt transmembrane transporter activity [inference]

zinc ion transmembrane transporter activity

bicarbonate transmembrane transporter activity [inference]

monoatomic cation:bicarbonate symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

elongator complex

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
tRNA processing
tRNA wobble uridine modification

Displaying **all 4** entries
InterPro
Elongator complex protein 2
WD40 repeat
WD40-repeat-containing domain superfamily
WD40/YVTN repeat-like-containing domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
plasma membrane	PMID:12702650 PMID:15464587
basolateral plasma membrane	PMID:23322169
cell surface	PMID:12702650 PMID:16481356
membrane	FB:FBrf0231198

Ortholog

Displaying entries **1 - 10** of 19 in total

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Species	Gene ID	Alliance of Genome Resources
Caenorhabditis elegans	23516	WB:WBGene00021936
Danio rerio	25800	ZFIN:ZDB-GENE-030131-3023
Xenopus tropicalis	38976	Xenbase:XB-GENE-1221212
Rattus norvegicus	55630	RGD:1306701
Xenopus tropicalis	57181	Xenbase:XB-GENE-1221212
Caenorhabditis elegans	64116	WB:WBGene00021936
Caenorhabditis elegans	67547	WB:WBGene00021936
Xenopus tropicalis	72002	Xenbase:XB-GENE-952069
Rattus norvegicus	72027	RGD:1306701
Danio rerio	106957	ZFIN:ZDB-GENE-030131-3023