GlyCosmos Portal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi apparatus	IBA
collagen-containing extracellular matrix	IBA
endoplasmic reticulum	IBA IDA	20888931
extracellular space	IBA IDA	20888931
perinuclear region of cytoplasm	IDA	20888931

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

perinuclear region of cytoplasm

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GO Term	Evidence Code	PMID
procollagen galactosyltransferase activity	IMP	20888931
procollagen-lysine 5-dioxygenase activity	IBA ISS
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
procollagen glucosyltransferase activity	IMP	20888931
iron ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

dioxygenase activity [inference]

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

procollagen galactosyltransferase activity

hexosyltransferase activity [inference]

galactosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

procollagen galactosyltransferase activity

glucosyltransferase activity [inference]

procollagen glucosyltransferase activity

catalytic activity, acting on a protein [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

procollagen-lysine 2-oxoglutarate 5-dioxygenase 2

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
L-ascorbic acid binding
dioxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
procollagen-proline 4-dioxygenase activity

Displaying **all 4** entries
InterPro
Oxoglutarate/iron-dependent dioxygenase
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Prolyl 4-hydroxylase, alpha subunit
Prolyl 4-hydroxylase

Alliance of Genome Resources

Expression

Displaying **all 4** entries
Location	References
perinuclear region of cytoplasm	PMID:20888931
extracellular space	PMID:20888931
membrane	FB:FBrf0231198
endoplasmic reticulum	PMID:20888931

Rhea

RHEA:16569

O₂ + 2-oxoglutarate

CO₂ + succinate

Enzyme

1.14.11.4

PMID

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0060231	Bruck syndrome	Alliance of Genome Resources
DOID:0080734	Ehlers-Danlos syndrome kyphoscoliotic type 1	Alliance of Genome Resources
DOID:13359	Ehlers-Danlos syndrome	Alliance of Genome Resources
DOID:1459	hypothyroidism	Alliance of Genome Resources
DOID:3910	lung adenocarcinoma	Alliance of Genome Resources
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 53 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	5351	HGNC:9081
Homo sapiens	5352	HGNC:9082
Homo sapiens	8985	HGNC:9083
Mus musculus	18822	MGI:99907
Rattus norvegicus	24958	RGD:3353
Mus musculus	26432	MGI:1347007
Mus musculus	26433	MGI:1347008
Rattus norvegicus	116552	RGD:621382
Caenorhabditis elegans	174564	WB:WBGene00002497
Rattus norvegicus	288583	RGD:631339

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements