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lymphocyte cytosolic protein 1

Summary

Gene Symbol

LCP1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3936

KEGG Gene ID

PubChem

3936

Alliance of Genome Resources

HGNC:6528

Annotation

Keyword

3D-structure
Acetylation
Actin-binding
Alternative splicing
Calcium
Cell junction
Cell membrane
Cell projection
Chromosomal rearrangement
Cytoskeleton
Direct protein sequencing
Disease variant
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
P13796	L-plastin LC64P Lymphocyte cytosolic protein 1

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
T cell activation involved in immune response	IDA
obsolete protein kinase A signaling
cell migration	IMP
cortical actin cytoskeleton organization	ISS
animal organ regeneration	IEA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

actin filament-based process [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization

cell motility [inference]

cell migration

wound healing, spreading of cells

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

cortical actin cytoskeleton organization

cortical cytoskeleton organization [inference]

cortical actin cytoskeleton organization

cellular component assembly [inference]

actin filament bundle assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

T cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

developmental process [inference]

anatomical structure development [inference]

regeneration [inference]

animal organ regeneration

animal gross anatomical part developmental process [inference]

animal organ development [inference]

animal organ regeneration

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport

regulation of protein transport [inference]

regulation of intracellular protein transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport

regulation of cellular process [inference]

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport

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GO Term	Evidence Code	PMID
stress fiber	IMP
ruffle	ISS
ruffle	IMP
phagocytic cup	ISS
extracellular region	HDA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

cell projection membrane [inference]

ruffle membrane

cell junction

anchoring junction

cell-substrate junction [inference]

focal adhesion

leading edge membrane [inference]

ruffle membrane

actin filament bundle

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

filopodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

membraneless organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

actin cytoskeleton

intracellular organelle [inference]

intracellular membraneless organelle [inference]

cytoskeleton

actin cytoskeleton

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

perinuclear region of cytoplasm

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

actin filament

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GO Term	Evidence Code	PMID
actin binding	NAS
integrin binding	IPI
calcium ion binding	NAS
calcium ion binding	IEA
identical protein binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cytoskeletal protein binding [inference]

actin binding

actin filament binding

enzyme binding [inference]

GTPase binding

identical protein binding

cell adhesion molecule binding [inference]

integrin binding

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050742	nicotine dependence	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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