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Guidelines

MIRAGE

diacylglycerol O-acyltransferase 2

Summary

Gene Symbol

dgat2

Organism

Xenopus tropicalis (tropical clawed frog)

External Links

NCBI Gene

395003

PubChem

395003

Alliance of Genome Resources

Xenbase:XB-GENE-1017054

Annotation

Keyword

Acyltransferase
Cytoplasm
Endoplasmic reticulum
Glycerol metabolism
Lipid biosynthesis
Lipid droplet
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q6P342	Acyl-CoA retinol O-fatty-acyltransferase Diglyceride acyltransferase 2
A0A8J1J1E6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

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2
GO Term	Evidence Code	PMID
triglyceride biosynthetic process	IBA
triglyceride biosynthetic process	IEA
diacylglycerol metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

primary metabolic process [inference]

carbohydrate metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

lipid metabolic process

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

alditol metabolic process [inference]

glycerol metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

neutral lipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride biosynthetic process

diacylglycerol metabolic process

diacylglycerol biosynthetic process

monoacylglycerol metabolic process [inference]

monoacylglycerol biosynthetic process

acylglycerol biosynthetic process [inference]

glycerolipid biosynthetic process [inference]

acylglycerol biosynthetic process [inference]

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasm	IEA
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	ISS
endoplasmic reticulum membrane	IBA
endoplasmic reticulum membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle membrane [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

lipid droplet

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
diacylglycerol O-acyltransferase activity	ISS
diacylglycerol O-acyltransferase activity	IBA
diacylglycerol O-acyltransferase activity	IEA
O-acyltransferase activity	IEA
acyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

O-acyltransferase activity

acylglycerol O-acyltransferase activity [inference]

diacylglycerol O-acyltransferase activity

retinol O-fatty-acyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Acyltransferase

Functional Category

I: Lipid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
O-acyltransferase activity
diacylglycerol O-acyltransferase activity
transferase activity
triglyceride biosynthetic process

Displaying 1 entry
InterPro
Diacylglycerol acyltransferase

Ortholog

Displaying entries **1 - 10** of 15 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	67800	ZFIN:ZDB-GENE-050913-15
Saccharomyces cerevisiae S288C	68393	SGD:S000005771
Saccharomyces cerevisiae S288C	80168	SGD:S000005771
Xenopus laevis	84649	Xenbase:XB-GENE-6078761
Saccharomyces cerevisiae S288C	116255	SGD:S000005771
Saccharomyces cerevisiae S288C	233549	SGD:S000005771
Danio rerio	252900	ZFIN:ZDB-GENE-050913-15
Saccharomyces cerevisiae S288C	346606	SGD:S000005771
Saccharomyces cerevisiae S288C	347516	SGD:S000005771
Xenopus laevis	395003	Xenbase:XB-GENE-6078761

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025