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fibronectin leucine rich transmembrane protein 1

Summary

Gene Symbol

Flrt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

396184

PubChem

396184

Alliance of Genome Resources

MGI:3026647

Annotation

Keyword

Alternative initiation
Cell adhesion
Cell junction
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Developmental protein
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Leucine-rich repeat
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q6RKD8	Fibronectin leucine rich transmembrane protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
fibroblast growth factor receptor signaling pathway	IMP	16872596 20421966
neuron projection extension	IMP	20421966
dendrite development	IMP	20421966
cell adhesion	IEA
positive regulation of synapse assembly	IDA	24613359

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

dendrite development

developmental process [inference]

anatomical structure development [inference]

dendrite development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

neuron projection extension

developmental growth [inference]

developmental cell growth [inference]

neuron projection extension

developmental growth involved in morphogenesis [inference]

neuron projection extension

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

fibroblast growth factor receptor signaling pathway

regulation of cellular component biogenesis [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cellular component organization [inference]

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

positive regulation of synapse assembly

positive regulation of cell junction assembly [inference]

positive regulation of synapse assembly

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

positive regulation of nervous system development [inference]

positive regulation of synapse assembly

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasmic vesicle	IDA	20421966
focal adhesion	IDA	16872596
cytoplasmic vesicle membrane	IEA
endoplasmic reticulum membrane	IEA
neuronal cell body membrane	IDA	20421966

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

cell body membrane [inference]

neuronal cell body membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
fibroblast growth factor receptor binding	IPI	16872596

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

fibroblast growth factor receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Leucine-rich repeat

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 8** entries
InterPro
Cysteine-rich flanking region, C-terminal
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
Leucine-rich repeat N-terminal domain
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **1 - 10** of **125** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23769		HGNC:3760	HUMAN06801
Canis lupus familiaris	483767			CANLF06121
Rattus norvegicus	499308	10116_1:0008f9	RGD:1565152	RATNO19525
Macaca mulatta	717942			MACMU11622
Pan troglodytes	742718			PANTR03251
Bos taurus	788007			BOVIN23364
Ornithorhynchus anatinus	100085929			ORNAN18941
Danio rerio	100144397		ZFIN:ZDB-GENE-080327-6
Danio rerio	100144402		ZFIN:ZDB-GENE-080327-22
Equus caballus	100147627			HORSE05153