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activin A receptor type 2A

Summary

Gene Symbol

ACVR2A

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 396324
PubChem: 396324

Annotation

Keyword

ATP-binding
Cell membrane
Disulfide bond
Glycoprotein
Magnesium
Manganese
Metal-binding
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8V0Y294
Q90669	Activin receptor type IIA

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
protein phosphorylation	IEA	22301074 30032202
cell population proliferation
axis specification
activin receptor signaling pathway	IEA	30032202
mesodermal cell differentiation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

activin receptor signaling pathway

cell population proliferation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell differentiation [inference]

mesodermal cell differentiation

multicellular organismal process [inference]

pattern specification process [inference]

axis specification

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesodermal cell differentiation

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

activin receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm
plasma membrane	IEA	30032202
membrane
activin receptor complex	IEA	30032202

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

activin receptor complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

activin receptor complex

catalytic complex [inference]

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

protein kinase complex [inference]

serine/threonine protein kinase complex [inference]

activin receptor complex

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
transforming growth factor beta receptor activity
ATP binding	IEA	22301074 30032202
activin receptor activity	IEA	30032202
metal ion binding
activin binding	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

activin binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein kinase

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
activin binding
activin receptor activity
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transmembrane receptor protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase signaling pathway

Displaying **all 5** entries
InterPro
Protein kinase domain
Protein kinase-like domain superfamily
Ser/Thr protein kinase, TGFB receptor
Serine/threonine-protein kinase, active site
Snake toxin-like superfamily