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transforming growth factor beta 3

Summary

Gene Symbol

TGFB3

Organism

Gallus gallus (chicken)

External Links

NCBI Gene: 396438
PubChem: 396438

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Growth factor
Mitogen
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P16047

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
positive regulation of cell population proliferation
negative regulation of macrophage cytokine production
positive regulation of cell division
epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of collagen biosynthetic process

GO Hierarchy

biological process

cellular process [inference]

cell activation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction [inference]

SMAD protein signal transduction

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

epithelial to mesenchymal transition involved in endocardial cushion formation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

cell-cell junction organization

multicellular organismal process [inference]

cell activation

tissue migration [inference]

mesenchyme migration

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gland morphogenesis [inference]

salivary gland morphogenesis

face morphogenesis

anatomical structure development [inference]

tube development [inference]

digestive tract development [inference]

embryonic digestive tract development

animal organ development [inference]

hematopoietic or lymphoid organ development [inference]

spleen development

embryonic organ development [inference]

embryonic digestive tract development

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition [inference]

cardiac epithelial to mesenchymal transition

epithelial to mesenchymal transition involved in endocardial cushion formation

response to stimulus [inference]

response to stress [inference]

response to hypoxia

detection of hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

detection of oxygen [inference]

detection of hypoxia

response to decreased oxygen levels [inference]

response to hypoxia

detection of hypoxia

response to endogenous stimulus [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to progesterone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to steroid hormone [inference]

response to progesterone

response to organic cyclic compound [inference]

response to steroid hormone [inference]

response to progesterone

response to lipid [inference]

response to steroid hormone [inference]

response to progesterone

response to ketone [inference]

response to progesterone

response to oxygen-containing compound [inference]

response to ketone [inference]

response to progesterone

detection of stimulus [inference]

detection of chemical stimulus [inference]

detection of oxygen [inference]

detection of hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of collagen biosynthetic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of collagen biosynthetic process [inference]

positive regulation of collagen biosynthetic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of collagen biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of collagen metabolic process [inference]

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

regulation of collagen biosynthetic process [inference]

positive regulation of collagen biosynthetic process

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of collagen biosynthetic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of collagen metabolic process [inference]

positive regulation of collagen biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell division

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction [inference]

SMAD protein signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of production of molecular mediator of immune response [inference]

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cell population proliferation

regulation of cell differentiation [inference]

regulation of epithelial to mesenchymal transition [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell differentiation [inference]

positive regulation of epithelial to mesenchymal transition

positive regulation of cell division

positive regulation of cell motility [inference]

positive regulation of cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

negative regulation of production of molecular mediator of immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cell division [inference]

positive regulation of cell division

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of cytokine production involved in immune response [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

regulation of macrophage cytokine production [inference]

negative regulation of macrophage cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of epithelial to mesenchymal transition

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of cytokine production involved in immune response [inference]

negative regulation of macrophage cytokine production

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular matrix
extracellular region	IEA	30032202
extracellular space	IEA	22301074 30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
type II transforming growth factor beta receptor binding	IEA	30032202
type III transforming growth factor beta receptor binding	IEA	30032202
identical protein binding
cytokine activity	IEA	30032202
growth factor activity	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

receptor ligand activity [inference]

growth factor binding [inference]

transforming growth factor beta binding

cytokine binding [inference]

transforming growth factor beta binding

identical protein binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transforming growth factor beta-2

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
cytokine activity
growth factor activity
positive regulation of cell division
regulation of cell population proliferation
transforming growth factor beta receptor binding
transforming growth factor beta receptor signaling pathway

Displaying **all 6** entries
InterPro
Cystine-knot cytokine
TGF-beta, propeptide
Transforming growth factor beta, conserved site
Transforming growth factor-beta, C-terminal
Transforming growth factor-beta-related
Transforming growth factor-beta

Ortholog

Displaying entries **1 - 10** of 14 in total

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Species	Gene ID	OrthoDB
Meleagris gallopavo	100544554	9103_1:00168e
Anas platyrhynchos	101802287	8839_0:00199e
Anser cygnoides	106038869	8845_0:000ab6
Coturnix japonica	107315120	93934_0:001992
Numida meleagris	110401408	8996_0:001ad7
Phasianus colchicus	116228975	9054_0:00115e
Aythya fuligula	116490182	219594_0:00162a
Oxyura jamaicensis	118167829	8884_0:0017b0
Cygnus atratus	118244426	8868_0:0017b7
Cygnus olor	121071794	8869_0:001592

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements