GlyCosmos Portal

GlyTouCan

Glycan Structure Repository

GlyComb

Glycoconjugate Repository

GlycoPOST

Glycomics MS raw data Repository

UniCarb-DR

Glycomics MS Repository for glycan annotations from GlycoWorkbench

LM-GlycoRepo

Repository for lectin-assisted multimodality data

All Resources

Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

Other Information

Release Statistics Download

Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

low density lipoprotein receptor

Summary

Gene Symbol

LDLR

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 396801
PubChem: 396801

Annotation

Keyword

Cell membrane
Cholesterol metabolism
Coated pit
Disease variant
Disulfide bond
EGF-like domain
Endocytosis
Endosome
Glycoprotein
Golgi apparatus
LDL
Lipid transport
Lipoprotein
Lysosome
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
W0G5E7
Q28832

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
receptor-mediated endocytosis involved in cholesterol transport
cholesterol metabolic process
transcytosis
cholesterol homeostasis

GO Hierarchy

biological process

metabolic process [inference]

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

sterol metabolic process [inference]

cholesterol metabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

cholesterol metabolic process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

transcytosis

cellular localization [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

multicellular organismal process [inference]

transcytosis

homeostatic process [inference]

chemical homeostasis [inference]

lipid homeostasis [inference]

sterol homeostasis [inference]

cholesterol homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

transcytosis

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

receptor-mediated endocytosis involved in cholesterol transport

establishment of localization in cell [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

cellular localization [inference]

intracellular transport [inference]

receptor-mediated endocytosis involved in cholesterol transport

Displaying entries **6 - 8** of 8 in total

« First

‹ Prev

1

2
GO Term	Evidence Code	PMID
lysosome
low-density lipoprotein particle
clathrin-coated pit

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-lipid complex [inference]

lipoprotein particle [inference]

plasma lipoprotein particle [inference]

low-density lipoprotein particle

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
low-density lipoprotein particle receptor activity
lipoprotein particle binding
calcium ion binding	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding

cargo receptor activity [inference]

lipoprotein particle receptor activity [inference]

low-density lipoprotein particle receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Low-density lipoprotein receptor

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
calcium ion binding

Displaying **all 8** entries
InterPro
EGF-like calcium-binding domain
EGF-like calcium-binding, conserved site
EGF-like domain
LDL receptor-like superfamily
LDLR class B repeat
Low-density lipoprotein (LDL) receptor class A repeat
Low-density lipoprotein (LDL) receptor class A, conserved site
Six-bladed beta-propeller, TolB-like

Ortholog

Displaying entries **21 - 30** of 78 in total

« First

‹ Prev

1

2

3

4

5

6

7

8

Next ›

Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Pan paniscus	100974202			PANPA19517
Papio anubis	101016912			PAPAN22564
Felis catus	101080362			FELCA03085
Gorilla gorilla gorilla	101124590			GORGO15189
Tursiops truncatus	101334070	9739_0:000d21		TURTR05214
Jaculus jaculus	101607686			JACJA19188
Mustela putorius furo	101671487			MUSPF15214
Chrysemys picta bellii	101932535			CHRPI25241
Ictidomys tridecemlineatus	101956982			ICTTR17297
Chinchilla lanigera	102029196			CHILA19883

About Release Notes Help Feedback

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.1.0

Last updated: December 9, 2024