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plasminogen activator, tissue type

Summary

Gene Symbol

PLAT

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397121
PubChem: 397121

Annotation

Keyword

Cleavage on pair of basic residues
Disulfide bond
EGF-like domain
Glycoprotein
Kringle
Plasminogen activation
Reference proteome
Repeat
Secreted
Serine protease
Signal
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8SQ23

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
smooth muscle cell migration	IEA	30032202
plasminogen activation	IEA	22301074 30032202
platelet-derived growth factor receptor signaling pathway
prevention of polyspermy

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

protein maturation [inference]

protein processing [inference]

zymogen activation [inference]

plasminogen activation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

platelet-derived growth factor receptor signaling pathway

cell motility [inference]

cell migration [inference]

muscle cell migration [inference]

smooth muscle cell migration

reproductive process [inference]

prevention of polyspermy

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

platelet-derived growth factor receptor signaling pathway

regulation of reproductive process [inference]

regulation of fertilization [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074
extracellular space	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
serine-type endopeptidase activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

plasminogen activator, tissue type

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
hydrolase activity
plasminogen activation
platelet-derived growth factor receptor signaling pathway
proteolysis
serine-type endopeptidase activity
serine-type peptidase activity
smooth muscle cell migration

Displaying entries **1 - 10** of 13 in total

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InterPro
EGF-like domain
Fibronectin, type I
Kringle superfamily
Kringle, conserved site
Kringle-like fold
Kringle
Peptidase S1, PA clan, chymotrypsin-like fold
Peptidase S1, PA clan
Peptidase S1A, chymotrypsin family
Serine proteases, trypsin domain

Ortholog

Displaying entries **1 - 10** of 95 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	5327	HUMAN93634
Mus musculus	18791	MOUSE58565
Rattus norvegicus	25692	RATNO11263
Bos taurus	281407	BOVIN22160
Pan troglodytes	472748	PANTR42459
Canis lupus familiaris	482840	CANLF04655
Macaca mulatta	704475	MACMU43294
Oryctolagus cuniculus	100009556	RABIT14337
Monodelphis domestica	100033029	MONDO09164
Oryzias latipes	100049466	ORYLA17355