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flavin containing dimethylaniline monoxygenase 1

Summary

Gene Symbol

FMO1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397132
PubChem: 397132

Annotation

Keyword

Acetylation
Direct protein sequencing
Endoplasmic reticulum
FAD
Glycoprotein
Membrane
Monooxygenase
NADP
Reference proteome
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P16549	Dimethylaniline monooxygenase [N-oxide-forming] 1 Dimethylaniline oxidase 1 Hepatic flavin-containing monooxygenase 1 Trimethylamine monooxygenase
A0A480Y4M1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
organic acid metabolic process
toxin metabolic process
taurine biosynthetic process
NADPH oxidation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organonitrogen compound metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organonitrogen compound biosynthetic process [inference]

taurine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

sulfur compound biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

organonitrogen compound biosynthetic process [inference]

taurine biosynthetic process

secondary metabolic process [inference]

toxin metabolic process

cellular metabolic process [inference]

organic acid metabolic process

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

sulfur compound metabolic process [inference]

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

sulfur compound biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

toxin metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

sulfur compound biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

small molecule metabolic process [inference]

organic acid metabolic process

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

small molecule biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organic substance metabolic process [inference]

organic acid metabolic process

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organonitrogen compound metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organonitrogen compound biosynthetic process [inference]

taurine biosynthetic process

organic substance biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

organonitrogen compound biosynthetic process [inference]

taurine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

sulfur compound metabolic process [inference]

alkanesulfonate metabolic process [inference]

taurine metabolic process [inference]

taurine biosynthetic process

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

sulfur compound biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

toxin metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

cellular biosynthetic process [inference]

organic acid biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

sulfur compound biosynthetic process [inference]

alkanesulfonate biosynthetic process [inference]

taurine biosynthetic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

pyridine-containing compound metabolic process [inference]

pyridine nucleotide metabolic process [inference]

nicotinamide nucleotide metabolic process [inference]

NADP metabolic process [inference]

NADPH oxidation

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
N,N-dimethylaniline monooxygenase activity	IEA	22301074 30032202
trimethylamine monooxygenase activity
hypotaurine dehydrogenase activity
flavin adenine dinucleotide binding	IEA	22301074
NADP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [inference]

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

flavin adenine dinucleotide binding

ion binding [inference]

anion binding [inference]

flavin adenine dinucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NADP binding

flavin adenine dinucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

N-oxide-forming dimethylaniline monooxygenase

Functional Category

P: Inorganic ion transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
NADP binding
flavin adenine dinucleotide binding
monooxygenase activity
oxidoreductase activity

Displaying **all 2** entries
InterPro
FAD/NAD(P)-binding domain superfamily
Flavin monooxygenase-like

Ortholog

Displaying entries **1 - 10** of 58 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	2326	HUMAN53560
Mus musculus	14261	MOUSE28993
Rattus norvegicus	25256	RATNO07585
Canis lupus familiaris	403604	CANLF17258
Pan troglodytes	456444	PANTR23010
Bos taurus	508781	BOVIN08220
Macaca mulatta	703743	MACMU24480
Pongo abelii	100173722	PONAB19986
Taeniopygia guttata	100222819	TAEGU29641
Callithrix jacchus	100409221	CALJA16714

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