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fucosyltransferase 2 (H blood group)

Summary

Gene Symbol

FUT2

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397139
KEGG Gene ID: ssc:397139
PubChem: 397139

Annotation

Keyword

Direct protein sequencing
Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q10982	Alpha(1,2)FT 2 Fucosyltransferase 2 GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2 Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT2 Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
regulation of endothelial cell proliferation
carbohydrate metabolic process	IEA	22301074 30032202
protein glycosylation	IEA	30032202
glycolipid metabolic process
regulation of cell adhesion

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

glycosylation [inference]

fucosylation

macromolecule glycosylation [inference]

protein glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation

macromolecule glycosylation [inference]

protein glycosylation

carbohydrate derivative metabolic process [inference]

liposaccharide metabolic process [inference]

glycolipid metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell adhesion

regulation of cell population proliferation [inference]

regulation of epithelial cell proliferation [inference]

regulation of endothelial cell proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
Golgi cisterna membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

Golgi cisterna membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
galactoside 2-alpha-L-fucosyltransferase activity	IEA	22301074 30032202
alpha-(1,2)-fucosyltransferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

fucosyltransferase activity [inference]

alpha-(1,2)-fucosyltransferase activity

galactoside 2-alpha-L-fucosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00718

Name

galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69]

References

Reactions

Displaying entries **1 - 10** of 12 in total

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KEGG Reaction	Enzyme	Acceptor	Product
R06090	2.4.1.69	G28261RX	G87164WU
R06170	2.4.1.69	G56390QA	G63238VS
R06024	2.4.1.69	G58896AZ	G13636IT
R06041	2.4.1.69	G33816GC	G59724US
R06035	2.4.1.69	G84034JH	G66427ZQ
R06031	2.4.1.69	G64885AH	G58990QD
R06027	2.4.1.-	G60645OK	G77593JU
R06089	2.4.1.69	G98726UE	G28261RX
R06086	2.4.1.69	G98900YM	G87164WU
R06156	2.4.1.69	G00049MO	G00050MO

Rhea

RHEA:50668

a β-D-galactosyl-(1→4)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→4)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.344

PMID

RHEA:50664

a β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl derivative + GDP-β-L-fucose

an α-L-Fuc-(1→2)-β-D-Gal-(1→3)-β-D-GlcNAc derivative + H⁺ + GDP

Enzyme

2.4.1.69

PMID

RHEA:32175

a β-D-Gal-(1→3)-β-D-GlcNAc-(1→3)-β-D-Gal-(1→4)-β-D-Glc-(1↔1ʼ)-Cer(d18:1(4E)) + GDP-β-L-fucose

H⁺ + α-L-fucosyl-(1→2)- β-D-galactosyl-(1→3)-N-acetyl-β-D-glucosaminyl-(1→3)-β-D-galactosyl-(1→4)-β-D-glucosyl-(1↔1ʼ)-N-acylsphing-4-enine + GDP

Enzyme

2.4.1.69

PMID

Ortholog

Displaying entries **21 - 30** of 38 in total

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Species	Gene ID	Orthologous MAtrix
Ictidomys tridecemlineatus	101974597	ICTTR05975
Capra hircus	102185028	CAPHI09365
Myotis lucifugus	102425138	MYOLU19681
Myotis lucifugus	102433448	MYOLU17445
Callorhinchus milii	103173436	CALMI48106
Callorhinchus milii	103183767	CALMI28296
Callorhinchus milii	103183768	CALMI28295
Callorhinchus milii	103183770	CALMI48106
Chlorocebus sabaeus	103234986	CHLSB15995
Nannospalax galili	103743625	NANGA12379

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

KEGG BRITE Database

International Collaboration

Acknowledgements