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ectonucleoside triphosphate diphosphohydrolase 1

Summary

Gene Symbol

ENTPD1

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397298
PubChem: 397298

Annotation

Keyword

ATP-binding
Calcium
Direct protein sequencing
Disulfide bond
Glycoprotein
Hydrolase
Magnesium
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9MYU4	ATP diphosphohydrolase Ecto-ATP diphosphohydrolase 1 Ecto-apyrase Lymphoid cell activation antigen Nucleoside triphosphate diphosphohydrolase 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleoside diphosphate catabolic process	IEA	30032202
platelet aggregation

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic substance catabolic process [inference]

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

homotypic cell-cell adhesion [inference]

platelet aggregation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

organophosphate catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate catabolic process

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

nucleoside phosphate catabolic process [inference]

nucleoside diphosphate catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
caveola

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

plasma membrane raft [inference]

caveola

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft [inference]

caveola

Displaying entries **11 - 14** of 14 in total

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GO Term	Evidence Code	PMID
ADP phosphatase activity
nucleoside diphosphate phosphatase activity
UDP phosphatase activity	IEA	30032202
ITPase activity

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

apyrase activity

nucleoside diphosphate phosphatase activity

ribonucleoside triphosphate phosphatase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ectonucleoside triphosphate diphosphohydrolase

Functional Category

F: Nucleotide transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ATP binding
hydrolase activity
nucleotide binding

Displaying 1 entry
InterPro
Nucleoside phosphatase GDA1/CD39

Rhea

RHEA:36795

H₂O + a ribonucleoside 5'-triphosphate

H⁺ + phosphate + a ribonucleoside 5'-phosphate

Enzyme

3.6.1.5

PMID

RHEA:64912

H₂O + a 2'-deoxyribonucleoside 5'-triphosphate

H⁺ + phosphate + a 2'-deoxyribonucleoside 5'-phosphate

Enzyme

3.6.1.5

PMID

15576788

Ortholog

Displaying entries **31 - 40** of 96 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Octodon degus	101569522		OCTDE02831
Mustela putorius furo	101685170		MUSPF14781
Ficedula albicollis	101817605		FICAL01312
Melopsittacus undulatus	101873834		MELUD14072
Chrysemys picta bellii	101948660		CHRPI10808
Ictidomys tridecemlineatus	101974791		ICTTR16918
Chinchilla lanigera	102010183		CHILA21068
Macaca fascicularis	102132860		MACFA43077
Capra hircus	102189182	9925_0:0044f4	CAPHI17921
Bos mutus	102270483	72004_1:0025ee

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OrthoDB (Group)

International Collaboration

Acknowledgements