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deoxyribonuclease 2, lysosomal

Summary

Gene Symbol

DNASE2

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397398
PubChem: 397398

Annotation

Keyword

Apoptosis
Developmental protein
Direct protein sequencing
Disulfide bond
Endonuclease
Glycoprotein
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
O62855	Acid DNase Deoxyribonuclease II alpha Lysosomal DNase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
apoptotic DNA fragmentation	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

DNA catabolic process [inference]

apoptotic DNA fragmentation

Displaying 1 entry
GO Term	Evidence Code	PMID
lysosome

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying 1 entry
GO Term	Evidence Code	PMID
deoxyribonuclease II activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity [inference]

endonuclease activity [inference]

DNA endonuclease activity [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

DNA nuclease activity [inference]

DNA endonuclease activity [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA nuclease activity [inference]

DNA endonuclease activity [inference]

DNA endonuclease activity, producing 3'-phosphomonoesters [inference]

deoxyribonuclease II activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Deoxyribonuclease-2

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
deoxyribonuclease II activity
hydrolase activity

Displaying 1 entry
InterPro
Deoxyribonuclease II

Ortholog

Displaying entries **11 - 20** of 78 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100388793			CALJA23355
Ailuropoda melanoleuca	100478733			AILME10964
Nomascus leucogenys	100599185			NOMLE02339
Loxodonta africana	100657160			LOXAF11723
Cavia porcellus	100728975			CAVPO15825
Cricetulus griseus	100763100			CRIGR09341
Otolemur garnettii	100953706			OTOGA05102
Pan paniscus	100983965			PANPA19629
Papio anubis	101004076			PAPAN23421
Saimiri boliviensis boliviensis	101044247			SAIBB35421

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024