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hypocretin receptor 2

Summary

Gene Symbol

HCRTR2

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397428
PubChem: 397428

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
O62809	Hypocretin receptor type 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	IEA	22301074 30032202
phospholipase C-activating G protein-coupled receptor signaling pathway
neuropeptide signaling pathway
feeding behavior	IEA	22301074
regulation of circadian sleep/wake cycle, wakefulness

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

multicellular organismal process [inference]

behavior [inference]

rhythmic behavior [inference]

circadian behavior [inference]

circadian sleep/wake cycle process

feeding behavior

locomotion

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration

rhythmic process [inference]

circadian rhythm [inference]

circadian behavior [inference]

circadian sleep/wake cycle process

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

cellular response to hormone stimulus

cellular response to endogenous stimulus [inference]

cellular response to hormone stimulus

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

cellular response to hormone stimulus

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to hormone stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of circadian rhythm [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, wakefulness

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

regulation of multicellular organismal process [inference]

regulation of behavior [inference]

regulation of circadian sleep/wake cycle [inference]

regulation of circadian sleep/wake cycle, wakefulness

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
orexin receptor activity	IEA	22301074
peptide binding

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

orexin receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

G protein-coupled peptide receptor activity [inference]

orexin receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Neuropeptide CCHamide-1 receptor

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM

Ortholog

Displaying entries **1 - 10** of 67 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	3062	HUMAN85259
Rattus norvegicus	25605	RATNO41214
Mus musculus	387285	MOUSE60562
Canis lupus familiaris	399545	CANLF02870
Pan troglodytes	462786	PANTR38432
Bos taurus	529603	BOVIN18219
Danio rerio	561260	DANRE05668
Macaca mulatta	711662	MACMU34373
Taeniopygia guttata	100229747	TAEGU20464
Oryctolagus cuniculus	100344413	RABIT02551

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

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Acknowledgements