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transforming growth factor beta receptor 3

Summary

Gene Symbol

TGFBR3

Organism

Sus scrofa (pig)

External Links

NCBI Gene: 397512
PubChem: 397512

Annotation

Keyword

Cell membrane
Disulfide bond
Extracellular matrix
Proteoglycan
Receptor
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P35054	Betaglycan Transforming growth factor beta receptor III

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway
response to follicle-stimulating hormone
regulation of transforming growth factor beta receptor signaling pathway
cell migration
epithelial to mesenchymal transition

GO Hierarchy

biological process

immune system process [inference]

immune response

cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

cell motility [inference]

cell migration

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

epithelial to mesenchymal transition

response to stimulus [inference]

immune response

response to endogenous stimulus [inference]

response to hormone [inference]

response to gonadotropin [inference]

response to follicle-stimulating hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to gonadotropin [inference]

response to follicle-stimulating hormone

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

intracellular signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
external side of plasma membrane
membrane
collagen-containing extracellular matrix
extracellular region

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

side of membrane [inference]

external side of plasma membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
type II transforming growth factor beta receptor binding
heparin binding
transforming growth factor beta receptor activity
coreceptor activity
transforming growth factor beta receptor activity, type III

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding

type II transforming growth factor beta receptor binding

growth factor binding [inference]

transforming growth factor beta binding

cytokine binding [inference]

transforming growth factor beta binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding

heparin binding

sulfur compound binding [inference]

heparin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type III

coreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transforming growth factor beta receptor type 3

Functional Category

I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
cell migration
epithelial to mesenchymal transition
glycosaminoglycan binding
regulation of transforming growth factor beta receptor signaling pathway
transforming growth factor beta binding
transforming growth factor beta receptor activity
transforming growth factor beta receptor signaling pathway
type II transforming growth factor beta receptor binding

Displaying **all 2** entries
InterPro
Zona pellucida domain
Zona pellucida, ZP-C domain

Ortholog

Displaying entries **1 - 10** of **105** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	7049		HUMAN50727
Mus musculus	21814		MOUSE43743
Rattus norvegicus	29610		RATNO08347
Pan troglodytes	457016		PANTR21562
Canis lupus familiaris	490163		CANLF16920
Macaca mulatta	705053		MACMU22099
Bos taurus	784894	9913_0:00089a	BOVIN26531
Monodelphis domestica	100026705		MONDO09531
Ornithorhynchus anatinus	100075992		ORNAN19504
Taeniopygia guttata	100218701		TAEGU28966