lipase A, lysosomal acid type
| UniProt | Protein Name |
|---|---|
| A0A0A0MT32 |
|
| P38571 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitotic cell cycle | ||
| cell morphogenesis | ||
| endothelial cell proliferation | ||
| response to dietary excess | ||
| hematopoietic progenitor cell differentiation |
| GO Term | Evidence Code | PMID |
|---|---|---|
| fibrillar center | ||
| nucleoplasm | ||
| lysosome | ||
| cytosol | ||
| lysosomal lumen |
| GO Term | Evidence Code | PMID |
|---|---|---|
| sterol esterase activity | ||
| sterol esterase activity | ||
| sterol esterase activity | ||
| sterol esterase activity | ||
| lipase activity |
| Gene Ontology |
|---|
| hydrolase activity, acting on ester bonds |
| lipid metabolic process |
| InterPro |
|---|
| Alpha/Beta hydrolase fold |
| Lipase, eukaryotic |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080217 | lysosomal acid lipase deficiency | |
| DOID:14497 | Wolman disease | |
| DOID:14502 | cholesterol ester storage disease |
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000846 | Adrenal insufficiency |
| HP:0000952 | Jaundice |
| HP:0000989 | Pruritus |
| HP:0001263 | Global developmental delay |
| HP:0001394 | Cirrhosis |
| HP:0001395 | Hepatic fibrosis |
| HP:0001397 | Hepatic steatosis |
| HP:0001399 | Hepatic failure |
| HP:0001405 | Periportal fibrosis |
| Disease ID | Disease Name |
|---|---|
| OMIM:620151 |
|
| ORPHA:75233 |
|
| OMIM:278000 |
|
| ORPHA:75234 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3988 | Xenbase:XB-GENE-952977 | ||
| 8513 | ZFIN:ZDB-GENE-040426-2737 | ||
| 16889 | Xenbase:XB-GENE-952977 | MOUSE25397 | |
| 25055 | RATNO18467 | ||
| 41643 | Xenbase:XB-GENE-952977 | ||
| 43973 | Xenbase:XB-GENE-952977 | ||
| 50682 | SGD:S000001623 | ||
| 67717 | SGD:S000001623 | ||
| 70166 | SGD:S000001623 | ||
| 78753 | Xenbase:XB-GENE-952977 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.4.0
Last updated: December 8, 2025