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Gram-negative bacteria binding protein 1

Summary

Gene Symbol

GNBP1

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

40034

PubChem

40034

Alliance of Genome Resources

FB:FBgn0040323

Annotation

Keyword

Cell membrane
GPI-anchor
Innate immunity
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9NHB0
A0ZX68

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
pattern recognition receptor signaling pathway	IDA	10827089
innate immune response-activating signaling pathway	IDA	10827089
carbohydrate metabolic process	IEA
immune response	IEP	10827089
peptidoglycan catabolic process	IDA	17024181

GO Hierarchy

biological process

immune system process [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

Toll receptor ligand protein activation cascade

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

Toll receptor ligand protein activation cascade

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

Toll receptor ligand protein activation cascade

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan metabolic process [inference]

peptidoglycan metabolic process [inference]

peptidoglycan catabolic process

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

protein metabolic process [inference]

protein maturation [inference]

protein activation cascade [inference]

Toll receptor ligand protein activation cascade

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

glycosaminoglycan catabolic process [inference]

peptidoglycan catabolic process

cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

defense response to bacterium [inference]

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to bacterium [inference]

immune response

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

defense response to bacterium [inference]

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus

defense response to other organism [inference]

defense response to bacterium [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of innate immune response

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of innate immune response

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of innate immune response

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of immune response [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of innate immune response

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of immune response [inference]

activation of immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of innate immune response

positive regulation of innate immune response [inference]

activation of innate immune response [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

immune response-regulating signaling pathway [inference]

immune response-activating signaling pathway [inference]

innate immune response-activating signaling pathway

pattern recognition receptor signaling pathway

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IDA	10827089
extracellular space	IDA	14684822
plasma membrane	IDA	10827089
side of membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

side of membrane

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	IDA	10827089 16385003
(1->3)-beta-D-glucan binding	IDA	10827089 16385003
protein binding	IPI	17024181
hydrolase activity	IMR	10827089
hydrolase activity	IKR	10827089

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

beta-glucanase activity

binding [inference]

protein binding

lipid binding [inference]

lipopolysaccharide binding

carbohydrate binding

polysaccharide binding [inference]

(1->3)-beta-D-glucan binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

glycosaminoglycan binding [inference]

peptidoglycan binding

molecular transducer activity [inference]

signaling receptor activity [inference]

pattern recognition receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Beta-1,3-glucan-binding protein

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 4** entries
InterPro
Beta-1,3-glucan-binding protein, N-terminal domain superfamily
Beta-1,3-glucan-binding protein, N-terminal
Concanavalin A-like lectin/glucanase domain superfamily
Glycoside hydrolase family 16

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
extracellular space	PMID:14684822
extracellular region	PMID:10827089
plasma membrane	PMID:10827089

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP008964
Gene Name: Gram-negative bacteria binding protein 1

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements