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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leukotriene C4 synthase
Summary
- Gene Symbol
-
- LTC4S
- Aliases
-
- MGC33147
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Endoplasmic reticulum
- Leukotriene biosynthesis
- Lipid biosynthesis
- Lyase
- Nucleus
- Phosphoprotein
- Reference proteome
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16873 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| leukotriene metabolic process | ||
| leukotriene biosynthetic process | ||
| cellular oxidant detoxification | ||
| long-chain fatty acid biosynthetic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear membrane | ||
| membrane |
|
|
| endoplasmic reticulum membrane | ||
| intracellular membrane-bounded organelle |
|
|
| nuclear outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| enzyme activator activity | ||
| identical protein binding | ||
| lipid binding | ||
| glutathione transferase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Rho GTPase-activating protein
- Functional Category
-
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| glutathione transferase activity |
Rhea
Disease
- Disease Ontology
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000252 | Microcephaly |
| HP:0001252 | Hypotonia |
| HP:0001263 | Global developmental delay |
| HP:0001522 | Death in infancy |
| HP:0001531 | Failure to thrive in infancy |
| Disease ID | Disease Name |
|---|---|
| OMIM:614037 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002479
- Gene Name
- leukotriene C4 synthase
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 17001 | MGI:107498 | MOUSE04754 | ||
| 114097 | RGD:620677 | |||
| 495166 | Xenbase:XB-GENE-981582 | |||
| 511749 | BOVIN32046 | |||
| 607316 | CANLF01974 | |||
| 705233 | MACMU39557 | |||
| 739986 | 9598_0:0017a5 | |||
| 100032154 | MONDO05921 | |||
| 100127769 | Xenbase:XB-GENE-981579 | |||
| 100456952 | 9601_0:001996 |
