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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
leukotriene C4 synthase
Summary
- Gene Symbol
-
- LTC4S
- Aliases
-
- MGC33147
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Direct protein sequencing
- Endoplasmic reticulum
- Leukotriene biosynthesis
- Lipid biosynthesis
- Lyase
- Nucleus
- Phosphoprotein
- Reference proteome
- Transferase
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16873 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| leukotriene biosynthetic process | ||
| leukotriene metabolic process | ||
| long-chain fatty acid biosynthetic process | ||
| cellular oxidant detoxification |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear envelope | ||
| intracellular membrane-bounded organelle |
|
|
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane | ||
| nuclear outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| lipid binding | ||
| glutathione peroxidase activity | ||
| leukotriene-C4 synthase activity | ||
| enzyme activator activity | ||
| protein binding |
GO Hierarchy
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11870 | Pick's disease | |
| DOID:12704 | ataxia telangiectasia | |
| DOID:1287 | cardiovascular system disease | |
| DOID:13003 | vertebrobasilar insufficiency | |
| DOID:1389 | polyneuropathy | |
| DOID:13922 | eosinophilic esophagitis | |
| DOID:14221 | abdominal obesity-metabolic syndrome 1 | |
| DOID:1443 | cerebral degeneration | |
| DOID:14525 | Reye syndrome | |
| DOID:1555 | urticaria |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000252 | Microcephaly |
| HP:0001252 | Hypotonia |
| HP:0001263 | Global developmental delay |
| HP:0001522 | Death in infancy |
| HP:0001531 | Failure to thrive in infancy |
| Disease ID | Disease Name |
|---|---|
| OMIM:614037 |
|
PubChem Disease
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
LIPID MAPS Gene / Proteome Database
- LMPD ID
- LMP002479
- Gene Name
- leukotriene C4 synthase
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 110216768 | PHACI12911 | ||
| 111235924 | SERDU28487 | ||
| 108411694 | PYGNA32237 | ||
| 101956036 | ICTTR03580 | ||
| 101594700 | JACJA18409 | ||
| 118319425 | SCOMX05037 | ||
| 117016804 | RHIFE23177 | ||
| 103245108 | CHLSB11290 | ||
| 108523369 | RHIBE38165 | ||
| 104676203 | RHIRO25910 |
