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lactotransferrin

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

4057

PubChem

4057

Alliance of Genome Resources

HGNC:6720

JoGo

LTF

TogoVar

LTF

Annotation

Keyword

3D-structure
Alternative promoter usage
Antibiotic
Cytoplasm
DNA-binding
Direct protein sequencing
Disulfide bond
Glycoprotein
Heparin-binding
Immunity
Iron transport
Isopeptide bond
Metal-binding
Nucleus
Osteogenesis
Proteomics identification
Reference proteome
Repeat
Secreted
Serine protease
Signal
Transcription regulation
Ubl conjugation

Proteins

Displaying **all 5** entries
UniProt	Protein Name
P02788	Growth-inhibiting protein 12 Talalactoferrin
Q2TUW9
V9HWI4
E7ER44
B3KSL2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **21 - 25** of 37 in total

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GO Term	Evidence Code	PMID
innate immune response	IMP	9596699
positive regulation of osteoblast differentiation	IDA	15166119
negative regulation of membrane potential	IMP	9596699
negative regulation of viral process	IMP	25193851
defense response to Gram-negative bacterium	IMP	15155221 9596699

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

humoral immune response

antimicrobial humoral response [inference]

innate immune response

innate immune response in mucosa

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

cellular process [inference]

cell killing [inference]

killing of cells of another organism

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

multicellular organismal process [inference]

ossification

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

bone morphogenesis

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with symbiont [inference]

modulation by host of symbiont process [inference]

modulation by host of viral process [inference]

negative regulation by host of viral process

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response

innate immune response in mucosa

defense response to fungus [inference]

antifungal humoral response

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response

innate immune response in mucosa

defense response to fungus [inference]

antifungal humoral response

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

humoral immune response

antimicrobial humoral response [inference]

innate immune response

innate immune response in mucosa

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response

innate immune response in mucosa

defense response to fungus [inference]

antifungal humoral response

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to bacterium [inference]

innate immune response

innate immune response in mucosa

defense response to fungus [inference]

antifungal humoral response

killing by host of symbiont cells [inference]

cytolysis by host of symbiont cells

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of protein metabolic process [inference]

regulation of proteolysis [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of biological process involved in symbiotic interaction [inference]

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of protein metabolic process [inference]

negative regulation of proteolysis [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

negative regulation of viral process

negative regulation of viral genome replication

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to external stimulus [inference]

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of response to external stimulus [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

positive regulation of defense response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of innate immune response [inference]

positive regulation of innate immune response [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of viral process [inference]

negative regulation of viral process

negative regulation of viral genome replication

regulation of viral life cycle [inference]

regulation of viral genome replication [inference]

negative regulation of viral genome replication

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of bone mineralization involved in bone maturation [inference]

positive regulation of bone mineralization involved in bone maturation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

regulation of osteoblast proliferation [inference]

positive regulation of osteoblast proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of pattern recognition receptor signaling pathway [inference]

positive regulation of toll-like receptor 4 signaling pathway

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of lipopolysaccharide-mediated signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of single-species biofilm formation in or on host organism [inference]

negative regulation of single-species biofilm formation in or on host organism

regulation of multicellular organismal process [inference]

regulation of cytokine production

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor superfamily cytokine production [inference]

regulation of tumor necrosis factor production

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of tumor necrosis factor (ligand) superfamily member 11 production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

regulation of ossification [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of bone mineralization involved in bone maturation [inference]

positive regulation of bone mineralization involved in bone maturation

positive regulation of ossification [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

positive regulation of multicellular organismal process [inference]

positive regulation of ossification [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production [inference]

negative regulation of tumor necrosis factor superfamily cytokine production [inference]

negative regulation of tumor necrosis factor (ligand) superfamily member 11 production

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of bone mineralization involved in bone maturation [inference]

positive regulation of bone mineralization involved in bone maturation

positive regulation of biomineral tissue development [inference]

positive regulation of bone mineralization [inference]

positive regulation of bone mineralization involved in bone maturation

regulation of hemopoiesis [inference]

regulation of myeloid cell differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of myeloid cell differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of leukocyte differentiation [inference]

regulation of myeloid leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

negative regulation of hemopoiesis [inference]

negative regulation of leukocyte differentiation [inference]

negative regulation of myeloid leukocyte differentiation [inference]

negative regulation of osteoclast differentiation [inference]

negative regulation of osteoclast development

regulation of osteoclast development [inference]

negative regulation of osteoclast development

regulation of biological quality [inference]

regulation of membrane potential [inference]

negative regulation of membrane potential

regulation of molecular function [inference]

regulation of ATP-dependent activity [inference]

negative regulation of ATP-dependent activity

negative regulation of molecular function [inference]

negative regulation of ATP-dependent activity

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

negative regulation of catalytic activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of hydrolase activity [inference]

negative regulation of hydrolase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of peptidase activity [inference]

negative regulation of peptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of endopeptidase activity [inference]

negative regulation of endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of cysteine-type endopeptidase activity [inference]

negative regulation of cysteine-type endopeptidase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of protein serine/threonine kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity [inference]

positive regulation of protein serine/threonine kinase activity

regulation of DNA-binding transcription factor activity [inference]

positive regulation of DNA-binding transcription factor activity [inference]

positive regulation of NF-kappaB transcription factor activity

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	IDA	12788072 17567961 18714013
extracellular space	IBA
extracellular space	HDA	16502470 22664934 23580065
nucleus	HDA	21630459

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

specific granule lumen

intracellular organelle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

specific granule lumen

endocytic vesicle lumen [inference]

phagocytic vesicle lumen

tertiary granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

secretory vesicle [inference]

secretory granule

specific granule

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

secretory vesicle [inference]

secretory granule

specific granule

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

secretory vesicle [inference]

secretory granule

specific granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
lipopolysaccharide binding	IDA	9596699
lipopolysaccharide binding	IMP	15155221
DNA binding	IEA
serine-type endopeptidase activity	IEA
cysteine-type endopeptidase inhibitor activity	IDA	12788072

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

binding [inference]

protein binding

lipid binding [inference]

lipopolysaccharide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

carbohydrate derivative binding [inference]

lipopolysaccharide binding

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

kinase regulator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

protein kinase regulator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

peptidase regulator activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

endopeptidase regulator activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

molecular function activator activity [inference]

enzyme activator activity [inference]

kinase activator activity [inference]

protein kinase activator activity [inference]

protein serine/threonine kinase activator activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

peptidase inhibitor activity [inference]

endopeptidase inhibitor activity [inference]

cysteine-type endopeptidase inhibitor activity

membrane destabilizing activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:1508	candidiasis	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources
DOID:4450	renal cell carcinoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

International Collaboration

Acknowledgements