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CD180 molecule

Summary

Gene Symbol

CD180

Organism

Homo sapiens (human)

External Links

NCBI Gene

4064

PubChem

4064

Alliance of Genome Resources

HGNC:6726

Annotation

Keyword

3D-structure
Cell membrane
Direct protein sequencing
Glycoprotein
Inflammatory response
Innate immunity
Leucine-rich repeat
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q99467	Lymphocyte antigen 64 Radioprotective 105 kDa protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
B cell proliferation involved in immune response	IBA
inflammatory response	IEA
lipopolysaccharide-mediated signaling pathway	IEA
positive regulation of lipopolysaccharide-mediated signaling pathway	IGI	10880523
positive regulation of lipopolysaccharide-mediated signaling pathway	IBA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

immune response [inference]

innate immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell activation [inference]

B cell activation involved in immune response [inference]

B cell proliferation involved in immune response

B cell proliferation [inference]

B cell proliferation involved in immune response

lymphocyte proliferation [inference]

B cell proliferation [inference]

B cell proliferation involved in immune response

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

innate immune response

immune response [inference]

innate immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to other organism [inference]

defense response to other organism [inference]

innate immune response

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to chemical [inference]

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

response to lipid [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to lipid [inference]

cellular response to lipopolysaccharide

cellular response to oxygen-containing compound [inference]

cellular response to lipopolysaccharide

cellular response to biotic stimulus [inference]

cellular response to molecule of bacterial origin [inference]

cellular response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of response to external stimulus [inference]

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of response to biotic stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of response to external stimulus [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

lipopolysaccharide-mediated signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

regulation of lipopolysaccharide-mediated signaling pathway [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of lipopolysaccharide-mediated signaling pathway

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
nucleoplasm	IDA
nucleolus	IDA
plasma membrane	IDA
extracellular matrix	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

spindle [inference]

mitotic spindle

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	21857663

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

CD180

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
B cell proliferation involved in immune response
cellular response to lipopolysaccharide
positive regulation of lipopolysaccharide-mediated signaling pathway

Displaying **all 4** entries
InterPro
Cysteine-rich flanking region, C-terminal
Leucine-rich repeat domain superfamily
Leucine-rich repeat, typical subtype
Leucine-rich repeat

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	3483	FB:FBgn0268063
Danio rerio	4064	ZFIN:ZDB-GENE-070705-323
Drosophila melanogaster	7098	FB:FBgn0268063
Drosophila melanogaster	10234	FB:FBgn0268063
Drosophila melanogaster	14723	FB:FBgn0268063
Mus musculus	17079	ZFIN:ZDB-GENE-070705-323	MOUSE10679
Drosophila melanogaster	79438	FB:FBgn0268063
Drosophila melanogaster	116135	FB:FBgn0268063
Drosophila melanogaster	218763	FB:FBgn0268063
Drosophila melanogaster	244152	FB:FBgn0268063

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements