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ras homolog gene family, member Ac

Summary

Gene Symbol

rhoac

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

406659

PubChem

406659

Alliance of Genome Resources

ZFIN:ZDB-GENE-040426-2665

Annotation

Keyword

Cell membrane
GTP-binding
Glycoprotein
Methylation
Prenylation
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7T2E8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
small GTPase mediated signal transduction	IEA
Rho protein signal transduction	IBA
cell migration	IBA
regulation of actin cytoskeleton organization	IBA
stress fiber assembly	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Ras protein signal transduction [inference]

Rho protein signal transduction

actin filament-based process [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization [inference]

actomyosin structure organization [inference]

stress fiber assembly

cellular component assembly [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

supramolecular fiber organization [inference]

actin filament organization [inference]

actin filament bundle organization [inference]

actin filament bundle assembly [inference]

contractile actin filament bundle assembly [inference]

stress fiber assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction

Ras protein signal transduction [inference]

Rho protein signal transduction

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization

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GO Term	Evidence Code	PMID
cytosol	IBA
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA
cleavage furrow	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane

plasma membrane

plasma membrane region [inference]

cleavage furrow

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

neuron spine [inference]

dendritic spine

postsynapse [inference]

dendritic spine

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GO Term	Evidence Code	PMID
nucleotide binding	IEA
GTPase activity	IBA
GTPase activity	IEA
GTP binding	IBA
GTP binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding [inference]

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

GTPase

Functional Category

T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying **all 4** entries
Gene Ontology
GTP binding
nucleotide binding
protein kinase binding
small GTPase-mediated signal transduction

Displaying **all 4** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Small GTPase Rho
Small GTPase

Ortholog

Displaying entries **1 - 10** of 34 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	387	Xenbase:XB-GENE-941426
Saccharomyces cerevisiae S288C	388	SGD:S000006369
Xenopus tropicalis	389	Xenbase:XB-GENE-941426
Xenopus tropicalis	406411	Xenbase:XB-GENE-941426
Xenopus tropicalis	406659	Xenbase:XB-GENE-941426
Xenopus tropicalis	436718	Xenbase:XB-GENE-941426
Xenopus tropicalis	856294	Xenbase:XB-GENE-941426
Saccharomyces cerevisiae S288C	100006041	SGD:S000006369
Ictalurus punctatus	100528424		ICTPU30033
Astyanax mexicanus	103027457		ASTMX20286

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements