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MIRAGE
SH2 domain containing 1A

Summary
Gene Symbol
  • SH2D1A
Organism
Homo sapiens (human)
NCBI Gene
4068
PubChem
4068
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Adaptive immunity
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Innate immunity
  • Reference proteome
  • SH2 domain
Proteins
Displaying 1 entry
UniProt Protein Name
O60880
  • Duncan disease SH2-protein
  • Signaling lymphocytic activation molecule-associated protein
  • T-cell signal transduction molecule SAP
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 9 in total
GO Term Evidence Code PMID
adaptive immune response
humoral immune response
cellular defense response
cell-cell signaling
natural killer cell activation
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Growth factor receptor-bound protein
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • M: Cell wall/membrane/envelope biogenesis
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
immune system process
regulation of immune response
Displaying all 2 entries
InterPro
SH2 domain superfamily
SH2 domain
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0060705 X-linked lymphoproliferative syndrome 1
Ortholog
Displaying entries 1 - 10 of 72 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
4068 Xenbase:XB-GENE-6076868
20400 MOUSE65069
574156 MACMU46860
612899 CANLF20129
613356 BOVIN36261
740507 PANTR46748
780420 PIGXX37963
100148259 DANRE06587
100195724 SALSA134731
100225606 TAEGU22428
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025