GlyCosmos Portal

Submissions

lysozyme

Summary

Gene Symbol

Aliases

renal amyloidosis

Organism

Homo sapiens (human)

External Links

NCBI Gene

4069

HGNC

6740

PubChem

4069

Alliance of Genome Resources

HGNC:6740

Annotation

Keyword

3D-structure
Amyloid
Amyloidosis
Bacteriolytic enzyme
Direct protein sequencing
Disease variant
Disulfide bond
Glycosidase
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P61626	1,4-beta-N-acetylmuramidase C
B2R4C5	1,4-beta-N-acetylmuramidase C

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
defense response to Gram-negative bacterium	IBA
killing of cells of another organism	IDA	9727055
defense response to bacterium	IDA	21093056
defense response to Gram-positive bacterium	IBA IDA	21093056
inflammatory response	TAS	366724

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response

metabolic process

cellular process [inference]

cell killing [inference]

killing of cells of another organism

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response

defense response to bacterium

disruption of anatomical structure in another organism [inference]

disruption of cell in another organism [inference]

killing of cells of another organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

antimicrobial humoral response

defense response to bacterium

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

antimicrobial humoral response

defense response to bacterium

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	HDA IDA TAS	16502470 21805676 22664934 23580065 2829884
tertiary granule lumen	TAS
extracellular exosome	HDA	19056867 19199708 23533145
azurophil granule lumen	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

azurophil granule lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

tertiary granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysozyme activity	IBA TAS	2829884
identical protein binding	IPI	23353684

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

lysozyme activity

peptidoglycan muralytic activity [inference]

lysozyme activity

binding [inference]

protein binding [inference]

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000090382

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

Disease

Disease Ontology

Displaying entries **181 - 187** of **187** in total

« First

‹ Prev

…

15

16

17

18

19
DO ID	Disease Name	Source
DOID:9471	meningitis	DisGeNET
DOID:950	dacryoadenitis	DisGeNET
DOID:9534	tuberculous pneumothorax	DisGeNET
DOID:9655	oral mucosa leukoplakia	DisGeNET
DOID:9663	aphthous stomatitis	DisGeNET
DOID:9741	biliary tract disease	DisGeNET
DOID:9938	dacryocystitis	DisGeNET

The Human Phenotype Ontology

Displaying entries **1 - 10** of 15 in total

1

2

Next ›

Last »
HPO ID	HPO Term
HP:0000006	Autosomal dominant inheritance
HP:0000093	Proteinuria
HP:0000100	Nephrotic syndrome
HP:0000112	Nephropathy
HP:0000790	Hematuria
HP:0000822	Hypertension
HP:0000969	Edema
HP:0000988	Skin rash
HP:0001396	Cholestasis
HP:0001744	Splenomegaly

Displaying 1 entry
Disease ID	Disease Name
OMIM:105200	familial visceral amyloidosis

PubChem Disease

MedGen Diseases

Familial visceral amyloidosis, Ostertag type

OMIM Phenotypes

AMYLOIDOSIS, FAMILIAL VISCERAL

KEGG Diseases

Familial amyloidosis

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying entries **1 - 10** of 88 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources
Drosophila melanogaster	31460	FB:FBgn0029765
Drosophila melanogaster	36798	FB:FBgn0034092
Drosophila melanogaster	37340	FB:FBgn0034538
Drosophila melanogaster	37341	FB:FBgn0034539
Drosophila melanogaster	38122	FB:FBgn0004431
Drosophila melanogaster	38125	FB:FBgn0004425
Drosophila melanogaster	38127	FB:FBgn0004427
Drosophila melanogaster	38128	FB:FBgn0004428
Drosophila melanogaster	38129	FB:FBgn0004429
Drosophila melanogaster	38130	FB:FBgn0004430

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

PubChem Disease

International Collaboration

Acknowledgements