GlyCosmos Portal

Submissions

NBR1 autophagy cargo receptor

Summary

Gene Symbol

NBR1

Organism

Homo sapiens (human)

External Links

NCBI Gene

4077

PubChem

4077

Alliance of Genome Resources

HGNC:6746

JoGo

NBR1

TogoVar

NBR1

Annotation

Keyword

3D-structure
Alternative splicing
Coiled coil
Cytoplasm
Cytoplasmic vesicle
Host-virus interaction
Lysosome
Phosphoprotein
Proteomics identification
Reference proteome
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q14596	Cell migration-inducing gene 19 protein Membrane component chromosome 17 surface marker 2 Neighbor of BRCA1 gene 1 protein Protein 1A1-3B
B7Z5R6

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
macroautophagy	IDA	19250911
macroautophagy	IBA
regulation of bone mineralization	ISS
regulation of stress-activated MAPK cascade	ISS
negative regulation of osteoblast differentiation	ISS

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

regulation of stress-activated MAPK cascade

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cellular response to stress [inference]

regulation of stress-activated protein kinase signaling cascade [inference]

regulation of stress-activated MAPK cascade

regulation of multicellular organismal process [inference]

regulation of ossification [inference]

regulation of bone mineralization

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

regulation of bone mineralization

Displaying entries **1 - 5** of 14 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
phagophore assembly site	IBA
nucleoplasm	IDA
mitochondrion	IDA	21296869
mitochondrial intermembrane space	IEA
lysosome	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

microbody membrane [inference]

peroxisomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

organelle envelope lumen [inference]

mitochondrial intermembrane space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome

autophagosome

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

mitochondrion

vacuole [inference]

lytic vacuole [inference]

lysosome

autophagosome

microbody [inference]

microbody membrane [inference]

peroxisomal membrane

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	19250911 19427866 19822672 20010802 20368287 20417604 20562859 20808283 24879152 25416956 26871637 29568061 30824926 32296183 33961781 34524948
zinc ion binding	IEA
ubiquitin binding	IDA	19427866
ubiquitin binding	IBA
mitogen-activated protein kinase binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding [inference]

mitogen-activated protein kinase binding

ubiquitin-like protein binding [inference]

ubiquitin binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

NBR1, autophagy cargo receptor

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
metal ion binding
ubiquitin binding
zinc ion binding

Displaying **all 7** entries
InterPro
Immunoglobulin-like fold
Next to BRCA1, central domain
PB1 domain
UBA-like superfamily
Ubiquitin-associated domain
Zinc finger, ZZ-type superfamily
Zinc finger, ZZ-type